作者机构：
[Luo, Kun; Xie, Can; Liu, Ting; Yuan, Xiaomin] College of Food Science and Engineering, Central South University of Forestry and Technology, Changsha, Hunan 410004, China;[Zhou, Liyi] College of Food Science and Engineering, Central South University of Forestry and Technology, Changsha, Hunan 410004, China. Electronic address: zhouly0817@163.com
通讯机构：
[Zhou, Liyi] C;College of Food Science and Engineering, Central South University of Forestry and Technology, Changsha, Hunan 410004, China. Electronic address:
关键词：
Cadmium ion;Enrichment and removal;Fluorescent probe;Functionalized glass slide
摘要：
Cadmium (Cd) is a widespread and highly toxic environmental pollutant, seriously threatening animal and plant growth. Therefore, monitoring and employing robust tools to enrich and remove Cd from the environment is a major challenge. In this work, by conjugating a fluorescent indicator (CCP) with a functionalized glass slide, a special composite material (CCPB) was constructed to enrich, remove, and monitor Cd(2+) in water rapidly. Then Cd(2+) could be effectively eluted by immersing the Cd-enriched CCPB in an ethylenediaminetetraacetic acid (EDTA) solution. With this, the CCPB was continuously reused. Its recovery of Cd(2+)was above and below 100 % after multiple uses by flame atomic absorption spectrometry (FAAS), which was excellent for practical use in enriching and removing Cd(2+) in real aqueous samples. Therefore, CCPB is an ideal material for monitoring, enriching, and removing Cd(2+) in wastewater, providing a robust tool for future practical applications of Cd enrichment and removal in the environment.
摘要：
The deterioration of food freshness and occurrence of spoilage is attributed to adverse external conditions during storage, leading to unnecessary waste and posing food safety concerns. Therefore, it is imperative to develop packaging that monitors and maintains food freshness. Intelligent and active packaging precisely meets these desired requirements. Intelligent packaging has the potential to offer real-time feedback on environmental changes within the packaging, providing valuable information about food quality and safety. On the other hand, active packaging represents a novel approach that incorporates active ingredients, such as antimicrobials into packages to enhance food quality. This review highlights recent advancements in dual -functional packaging utilizing various plant essential oils and pH -sensitive natural pigments. It explores different methods, with a focus on electrospinning, and also discusses existing challenges and future trends. This information aims to assist in the development of packaging systems, offering a new direction for the development of antibacterial and pHsensitive packaging.
作者机构：
[Dandan Qin; Zuomin Hu; Feiyan Yang; Tiantian Xie; Qi Wu; Han Lu; Weidan Guo; Xiuxiu Wu; Shuguo Sun; Feijun Luo] Hunan Key Laboratory of Grain-oil Deep Process and Quality Control, Hunan Key Laboratory of Forestry Edible Resources Safety and Processing, College of Food Science and Engineering, Central South University of Forestry and Technology, Changsha, Hunan, 410004, China
通讯机构：
[Shuguo Sun; Feijun Luo] H;Hunan Key Laboratory of Grain-oil Deep Process and Quality Control, Hunan Key Laboratory of Forestry Edible Resources Safety and Processing, College of Food Science and Engineering, Central South University of Forestry and Technology, Changsha, Hunan, 410004, China
摘要：
Myocardial ischemia-reperfusion (MI/R) not only causes cardiac damage, but also causes severe renal damage. T8 is the 8th peptide identified by peptiomics in digested yak milk dregs and our previous studies showed that T8 had strong antioxidant activity. This study evaluated the protective effects and molecular mechanisms of MI/R-induced kidney injury in rats. Our results indicated that peptide T8 could increase ejection fraction (EF) and shortened fraction (FS), and degraded ST segment elevation, which ameliorated cardiac function in the MI/R rats. Peptide T8 could increase activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-PX), and decreased the contents of malondialdehyde (MDA), serum creatinine (Scr) and blood urea nitrogen (BUN), which could ameliorate renal insufficiency. Peptide T8 and kidney injury-related targets in the MI/R-damaged rats were obtained from network pharmacology analysis. KEGG analysis revealed that T8 might affect 54 signaling pathways and 13 key targets were obtained by PPI network analysis. The binding affinity of peptide T8 to Keap1 was found to be the strongest by molecular docking analysis. In the H2O2-induced HEK293 cell model, peptide T8 decreased reactive oxygen species (ROS) content and changed the expression ratio of Bcl-2 and Bax, thereby inhibiting mitochondria-dependent apoptosis. Further studies indicated that T8 could regulate Nrf2 pathway and downstream target genes such as NQO1, which could reduce oxidative stress-induced damage. These results suggest that peptide T 8 can exert renal protection via regulating Nrf2 pathway and apoptosis-related genes.
摘要：
Octacosanol, a naturally occurring higher fatty alcohol, possessed numerous biological effects. However, octacosanol limited solubility in water due to its lipophilic nature and large structure, resulting in poor absorption and low bioavailability. To overcome this challenge, we developed a simple, environmentally friendly, and energy-efficient O/W nanoemulsion synthesis process. The nanoemulsion achieved an average droplet size of approximately 30nm, exhibited excellent dispersibility and stability at room temperature for 60days, and showcased robust storage properties insensitive to ambient temperature, pH, NaCl, and sucrose. Remarkably, the preparation process of the nanoemulsion maintained the biological activity of octacosanol while demonstrating significantly enhancing antioxidant activity compared to octacosanol suspension. Additionally, the nanoemulsion displayed negligible cytotoxic effects on Caco-2 cells. Significantly, the octacosanol nanoemulsion exhibited a 5.4-fold enhancement in transmembrane transport efficiency when compared to the suspension in Caco-2 cell monolayers. Additionally, in an in vivo experiment, there was a notable 2.9-fold increase in rat intestinal absorption. These findings could provide valuable insights into the development of octacosanol nanoemulsion, supporting its future applications and paving the way for the design of stable nanoemulsion systems for other lipophilic and sparingly soluble substances.
摘要：
Enzymatic hydrolysis lignin residues (EHLRs) of lignocellulose usually adsorbs cellulase, which can be recycled and used to replace parts of cellulase in the hydrolysis process. To understand this phenomenon during enzymatic hydrolysis (EH) of sugarcane bagasse (SCB) treated with sulfite (SPORL) and dilute acid (DA), the adsorption characteristics between lignin and cellulase in EHLRs were investigated, focusing on interaction force at molecular level and enzymatic activity. The results revealed that SPORL-EHLR adsorbed more beta-glucosidases (beta-GLs) through the stronger electrostatic attraction and hydrogen bond force, causing higher cellulase adsorption amount compared to DA-EHLR. Further exploration demonstrated that the cellobiose's catalytic and binding sites on beta-GLs were separated from the binding site of SPORL-EHLR on beta-GLs, resulting in minimal in-hibition of beta-GLs activity when bound to SPORL-EHLR. Furthermore, adding SPORL-EHLR in SCB hydrolysis saved 40% cellulase. This study deepens the understanding of the adsorption behavior between lignin and cellulase.
作者机构：
[Gu, Jiahui; Wang, Liyuan; Peng, Xianglian; Fu, Hongjun] College of Food Science and Engineering, National Engineering Laboratory for Deep Process of Rice and Byproducts, Central South University of Forestry and Technology, Changsha 41004, China;[Zhao, Jian] Food Science and Technology, School of Chemical Engineering, UNSW Australia, Sydney 2052, Australia
摘要：
In this work, we have developed a composite chitosan film incorporating the Litsea cubeba essential oil (LCEO) and starch with good physical properties, and investigated the effect of coating strawberries with this composite film. The best formula of the LCEO/chitosan/corn starch/glycerol (LCEO/CH/CS/gly) composite films is 0.25% LCEO, 2.75% CH, 0.40% corn starch, and 0.75% glycerol. Coating strawberries with CH/CS/gly film or LCEO/CH/CS/gly films resulted in significantly lower respiration intensity and a slower decay rate, much slower decreases in the firmness, and reductions in the sugar and ascorbic acid content of the fruit during storage (p < 0.05). The coatings also led to a much slower accumulation of malondialdehyde and anthocyanins (p < 0.05). The LCEO/CH/CS/gly film was generally more effective than the CH/CS/gly film; however, the effect was more obvious in the later stages of storage. Thus, coating strawberries with CH/CS/gly film or LCEO/CH/CS/gly film can be a viable method for extending the shelf-life of the fruit.
摘要：
This work innovatively used cellulose nanofibers as a photocatalyst carrier, which could recycle nano-photocatalysts and minimize nanoparticle aggregation. The morphology, structures, chemical composition, optical-electronic properties and photocatalytic performance of amino-modified carbon quantum dots-ZnO/cellulose nanofiber (N-CQDs-ZnO/CNF: ZCH-2) hydrogel were characterized by SEM, TEM, BET, EDS, XRD, FTIR, UV-vis, XPS, PL and other techniques. The mechanism of Cr(VI) adsorption synergistic photoreduction by ZCH-2 was discussed in detail. The results showed that the prepared ZCH-2 had excellent removal performance for Cr(VI). After 120min of adsorption and 40min of photoreduction, the removal efficiency of Cr(VI) was 98.9%. Compared with ZnO/CNF hydrogel, the adsorption performance of ZCH-2 increased by 268% and the photoreduction performance increased by 116%. The adsorption of Cr(VI) by ZCH-2 was controlled by electrostatic attraction and chemical adsorption. The photoreduction kinetic constant of ZCH-2 was 0.106min(-1), which was 8.9 times that of ZnO/CNF hydrogel. The N-CQDs in ZCH-2 could form N-CQDs-metal complexes with Cr(VI), resulting in fluorescence quenching, so Cr(VI) could be visually identified by fluorescence changes. This study provides a new idea for the design and optimization of a new multifunctional hydrogel with efficient adsorption-photoreduction-fluorescence recognition.
摘要：
Screening and identifying the active compounds in foods are important for the development and utilization of functional foods. In this study, the anti-enteritis activity of ethanol extract from Camellia oleifera oil (PECS) was quickly evaluated using a Smurf Drosophila model and the metabolomics approach, combined with molecular docking techniques, were performed to rapidly screen and identify compounds with potential anti-enteritis activity in PECS. PECS showed good anti-enteritis activity and inhibited the activity of 5-lipoxygenase (LOX), cyclooxygenase 2 (COX-2) and inducible nitric oxide synthase (iNOS). In particular, wighteone and p-octopamine were newly identified in C. oleifera oil and were proven to have good anti-enteritis activity. The inhibitory activity of kaempferitrin (IC(50) = 0.365 mmol L(-1)) was higher than that of wighteone (IC(50) = 0.424 mmol L(-1)) and p-octopamine (IC(50) = 0.402 mmol L(-1)). Of note, the IC(50) value of salazosulfapyridine was 0.810 mmol L(-1). Inhibition of LOX activity is likely one of the anti-enteritis mechanisms of PECS. These new findings lay the foundation for further investigations into the underlying mechanisms of anti-enteritis activity in C. oleifera oil.
作者机构：
School of Materials Science and Engineering, Central South University of Forestry and Technology, Changsha, China;College of Ocean Engineering and Energy, Guangdong Ocean University, Zhanjiang, China;School of Civil Engineering, Central South University of Forestry and Technology, Changsha, China;Hunan Engineering Research Center of Full Life-cycle Energy-efficient Buildings and Environmental Health, Changsha, China;[Dan Li] School of Food Science and Engineering, Central South University of Forestry and Technology, Changsha, China
通讯机构：
[Hanqing Wang; Jinping Zhao] S;School of Materials Science and Engineering, Central South University of Forestry and Technology, Changsha, China<&wdkj&>School of Civil Engineering, Central South University of Forestry and Technology, Changsha, China<&wdkj&>Hunan Engineering Research Center of Full Life-cycle Energy-efficient Buildings and Environmental Health, Changsha, China<&wdkj&>School of Civil Engineering, Central South University of Forestry and Technology, Changsha, China<&wdkj&>Hunan Engineering Research Center of Full Life-cycle Energy-efficient Buildings and Environmental Health, Changsha, China
关键词：
Food freezing;Magnetic field assistance;Freezing curve;Ice crystal;Shelf life;Low-temperature preservation
摘要：
Freezing is a widely used technology for food processing that not only lowers the temperature of food below its freezing point but also inhibits microbial activity and slows down biochemical reactions to enable long-term preservation. However, the freeze thawing cycle can cause various chemical and physical damages to food, which are the main influencing mechanisms of low-temperature preservation. The size of ice crystals determines the degree of physical damage to cells, which has a significant impact on the freezing quality. Magnetic field (MF) treatment is a physical method that has been found to be milder, more effective, and have no obvious side effects compared to chemical treatments. Numerous studies have reported that MF promotes the cold storage of food, prolongs shelf life, inhibits ice crystal nucleation, increases supercooling, accelerates freezing speed, and reduces ice crystal sizes significantly. However, the role of MF in ice nuclei formation is still unresolved, and there are inconsistencies in research results and a lack of clear understanding of its potential mechanism. This paper aims to introduce the influence of MF on the formation and growth of ice crystals, summarize freezing curves on water and salt solutions, and analyze MF applications from two aspects: the thermodynamic mechanism and molecular dynamics point of view for freezing processes. Additionally, it discusses the problems encountered in recent researches and presents future development trends. The conclusion can be drawn that MF demonstrates great application potential in the field of freezing processes and food quality attribute evaluation. However, many questions remain with little consensus in the literature regarding their roles, and the mechanism of action is not unified. The application of MF in food freezing processes is still challenging. This paper hopes to provide guidance for future work on food freezing and contribute to the advancement of this field.
摘要：
Efficient and comprehensive analysis of lipid profiles in yak ghee samples collected from different elevations is crucial for optimal utilization of these resources. Unfortunately, such research is relatively rare. Yak ghee collected from three locations at different altitudes (S2: 2986m; S5: 3671m; S6: 4508m) were analyzed by quantitative lipidomic. Our analysis identified a total of 176 lipids, and 147s lipid of them were upregulated and 29 lipids were downregulated. These lipids have the potential to serve as biomarkers for distinguishing yak ghee from different altitudes. Notably, S2 exhibited higher levels of fatty acids (21:1) and branched fatty acid esters of hydroxy fatty acids (14:0/18:0), while S5 showed increased levels of phosphatidylserine (O-20:0/19:1) and glycerophosphoric acid (19:0/22:1). S6 displayed higher levels of triacylglycerol (17:0/20:5/22:3), ceramide alpha-hydroxy fatty acid-sphingosine (d17:3/34:2), and acyl glucosylceramides (16:0-18:0-18:1). Yak ghee exhibited a high content of neutralizing glycerophospholipids and various functional lipids, including sphingolipids and 21 newly discovered functional lipids. Our findings provide insights into quantitative changes in yak ghee lipids during different altitudes, development of yak ghee products, and screening of potential biomarkers.
作者机构：
[Chen, Yingkang; Fu, Junwei; Wang, Jun; Liu, Min; Luo, Tao; Liao, Wanru; Wang, Qiyou; Liu, M; Li, Hongmei; Wang, Xiqing; Liu, Kang; Ni, Ganghai] Cent South Univ, Hunan Joint Int Res Ctr Carbon Dioxide Resource Ut, Sch Phys, State Key Lab Powder Met, Changsha 410083, Peoples R China.;[Liu, Changxu] Univ Exeter, Ctr Metamaterial Res & Innovat, Dept Engn, Exeter EX4 4QF, England.;[Wang, Yanqiu; Li, Wenzhang; Chen, Shanyong] Cent South Univ, Sch Chem & Chem Engn, Changsha 410083, Peoples R China.;[Chan, Ting-Shan] Natl Synchrotron Radiat Res Ctr, Hsinchu 300092, Taiwan.;[Ma, Chao] Hunan Univ, Coll Mat Sci & Engn, Changsha 410082, Peoples R China.
通讯机构：
[Liu, M ; Xi, BD ; Fu, JW] C;Cent South Univ, Hunan Joint Int Res Ctr Carbon Dioxide Resource Ut, Sch Phys, State Key Lab Powder Met, Changsha 410083, Peoples R China.;Chinese Res Inst Environm Sci, State Key Lab Environm Criteria & Risk Assessment, Beijing 100012, Peoples R China.
摘要：
Nitrate (NO(3)(‒)) pollution poses significant threats to water quality and global nitrogen cycles. Alkaline electrocatalytic NO(3)(‒) reduction reaction (NO(3)RR) emerges as an attractive route for enabling NO(3)(‒) removal and sustainable ammonia (NH(3)) synthesis. However, it suffers from insufficient proton (H(+)) supply in high pH conditions, restricting NO(3)(‒)-to-NH(3) activity. Herein, we propose a halogen-mediated H(+) feeding strategy to enhance the alkaline NO(3)RR performance. Our platform achieves near-100% NH(3) Faradaic efficiency (pH = 14) with a current density of 2 A cm(-2) and enables an over 99% NO(3)(-)-to-NH(3) conversion efficiency. We also convert NO(3)(‒) to high-purity NH(4)Cl with near-unity efficiency, suggesting a practical approach to valorizing pollutants into valuable ammonia products. Theoretical simulations and in situ experiments reveal that Cl-coordination endows a shifted d-band center of Pd atoms to construct local H(+)-abundant environments, through arousing dangling O-H water dissociation and fast *H desorption, for *NO intermediate hydrogenation and finally effective NO(3)(‒)-to-NH(3) conversion.
期刊：
International Journal of Biological Macromolecules,2024年261(Pt 2):129900 ISSN：0141-8130
通讯作者：
Li, Peng
作者机构：
[Sun, Xinyang; Wu, Simiao; Jiang, Xiaoyi; Shao, Zhiying; Fang, Yong] College of Food Science and Engineering, Nanjing University of Finance and Economics/Collaborative Innovation Center for Modern Grain Circulation and Safety, Nanjing, China;[Shao, Zhiying] Key Laboratory of Modern Agriculture Equipment and Technology, School of Agricultural Engineering, Jiangsu University, Zhenjiang, China;[Lin, Qinlu] College of Food Science and Engineering, Central South University of Forestry and Technology, Changsha, China;[Zhao, Siming] College of Food Science and Technology, Huazhong Agricultural University, Wuhan, China;[Cheng, Yunhui] College of Chemistry and Food Engineering, Changsha University of Science & Technology, Changsha, China
通讯机构：
[Li, Peng] C;College of Food Science and Engineering, Nanjing University of Finance and Economics/Collaborative Innovation Center for Modern Grain Circulation and Safety, Nanjing, China. Electronic address:
关键词：
Apple juice;Hg(II) removal;Nano‑selenium functionalized chitosan gel beads
摘要：
The presence of potentially toxic elements and compounds poses threats to the quality and safety of fruit juices. Among these, Hg(II) is considered as one of the most poisonous heavy metals to human health. Traditional chitosan-based and selenide-based adsorbents face challenges such as poor adsorption capacity and inconvenient separation in juice applications. In this study, we prepared nano‑selenium functionalized chitosan gel beads (nanoSe@CBs) and illustrated the synergistic promotions between chitosan and nanoSe in removing Hg(II) from apple juice. The preparation conditions, adsorption behaviors, and adsorption mechanism of nanoSe@CBs were systematically investigated. The results revealed that the adsorption process was primarily controlled by chemical adsorption. At the 0.1% dosage, the adsorbent exhibited high uptake, and the maximum adsorption capacity from the Langmuir isotherm model could reach 376.5mg/g at room temperature. The adsorbent maintained high adsorption efficiency (> 90%) across a wide range of Hg(II) concentrations (0.01 to 10mg/L) and was unaffected by organic acids present in apple juice. Additionally, nanoSe@CBs showed negligible effects on the quality of apple juice. Overall, nanoSe@CBs open up possibilities to be used as a safe, low-cost and highly-efficient adsorbent for the removal of Hg(II) from juices and other liquid foods.
摘要：
With the increase in people's living standards, the number of patients suffering from liver injury keeps on increasing. Traditional diagnostic methods can no longer meet the needs of early and accurate diagnosis due to their limitations in application. However, fluorescent probes based on different fluorophores and nanomaterials have been gradually lighting up medical research due to their unique properties, such as high specificity and non-invasiveness. In addition, accurate identification of the different types of liver injury biomarkers can significantly improve the level of early diagnosis. Therefore, this review reviews the fluorescent probes used in the detection of biomarkers of liver injury over recent years and briefly summarizes the corresponding biomarkers of different types of liver injury. Impressively, this review also lists the structures and the response mechanisms of the different probes, and concludes with an outlook, suggesting directions in which improvements can be made. Finally, we hope that this review will contribute to the further development of fluorescent probes for the early diagnosis and assessment of liver injury. With the increase in people's living standards, the number of patients suffering from liver injury keeps on increasing.
关键词：
Heavy metals;Magnetic material;Matrix effect;Multiple-ion adsorption;Trace concentration
摘要：
A one-pot synthesis afforded a magnetic, crosslinked polymer adsorbent (m-P6) with a variety of functional groups to realize simultaneous adsorption of Cd(2+), Pb(2+), Hg(2+), and As(3+). The material was characterized by TEM-EDS, XRD, FT-IR, VSM, and XPS. Kinetic and isothermal analyses suggested mainly chemisorption processes of heavy metal ions that form multiple layers on heterogeneous surfaces. Theoretical adsorption capacities calculated by a pseudo-2nd-order kinetic model and the Sips isothermal model were 282.88mg/g for Cd(2+), 326.18mg/g for Pb(2+), 117.85mg/g for Hg(2+), and 320.29mg/g for As(3+). m-P6 not only can efficiently adsorb divalent heavy metals (Cd(2+), Pb(2+), Hg(2+)), but also demonstrate a process of adsorption-driven catalytic oxidation by single-electron transfer (SET) from As(3+) to As(5+). In application, in addition to adsorption in water, m-P6 is capable of minimizing matrix interference, and extracting trace heavy metals in a complex environment (cereal) through easy operations for improving the detection accuracy, as well as it is potential for application in detection of trace heavy metals in foodstuffs. m-P6 can be readily regenerated and efficiently recycled for 5 cycles using eluent E12 and dilute acid.
期刊：
International Journal of Biological Macromolecules,2024年261(Pt 2):129879 ISSN：0141-8130
通讯作者：
Liu, Zhuxiang;Ren, Jiali
作者机构：
[Yang, Qiao; Huang, Xiaohui; Chang, Songlin] Hunan Key Laboratory of Forestry Edible Resources Safety and Processing, College of Food Science and Engineering, Central South University of Forestry and Technology, No. 498, Shaoshan Road, Changsha, Hunan 410004, China;[Huang, Xiaohui] Edible Fungi Institute, Changsha, Hunan 410013, China;[Wang, Xiaoyan; Liu, Yingwei] Edible Fungi Institute, Changsha, Hunan 410013, China;[Liu, Zhuxiang] College of Biological Resources and Environmental Sciences, Jishou University, Jishou, Hunan 416000, China. Electronic address: liuzhuxiang@126.com;[Ren, Jiali] Hunan Key Laboratory of Forestry Edible Resources Safety and Processing, College of Food Science and Engineering, Central South University of Forestry and Technology, No. 498, Shaoshan Road, Changsha, Hunan 410004, China. Electronic address: t20091483@csuft.edu.cn
通讯机构：
[Liu, Zhuxiang] C;[Ren, Jiali] H;College of Biological Resources and Environmental Sciences, Jishou University, Jishou, Hunan 416000, China. Electronic address:;Hunan Key Laboratory of Forestry Edible Resources Safety and Processing, College of Food Science and Engineering, Central South University of Forestry and Technology, No. 498, Shaoshan Road, Changsha, Hunan 410004, China. Electronic address:
关键词：
Osteoblasts proliferation and differentiation;Polysaccharide;Sparassis crispa;Structural characterization
摘要：
This study aimed to investigate the structural characterization of water-soluble polysaccharides from Sparassis crispa and their effects on the proliferation and differentiation of mouse osteoblasts. Three fractions (F-1, F-2, and F-3) were obtained from crude polysaccharides by a DEAE-52 cellulose column. The main fraction (F-1) was further purified by polysaccharide gel purification systems to obtain purified water-soluble Sparassis crispa polysaccharide (SCPS). The chemical structure of SCPS was analyzed by gas chromatography, Fourier transform infrared spectroscopy, methylation analysis, and nuclear magnetic resonance spectroscopy. The monosaccharide compositional analysis revealed that SCPS consisted of fucose, arabinose, galactose, glucose, xylose, mannose, ribose, galacturonic acid, glucuronic acid, and mannuronic acid in a molar ratio of 17.37:1.94:25.52:30.83:1.14:0.30:4.98:2.87:2.65. Moreover, the backbone of SCPS was composed of →3)-β-d-Glcp-(1→4)-β-d-Glcp-(1→, with side chains attached to the backbone at the O-6 positions through the →3,6)-β-d-Glcp-(1→ linkage. The in vitro experiments were conducted to investigate the effects of SCPS on the proliferation and differentiation of mouse osteoblasts. The results showed that SCPS significantly enhanced the proliferation and differentiation of mouse osteoblasts, indicating their potential as a pharmaceutical agent for promoting osteoblast proliferation and differentiation.
