作者机构：
[Jianjun Xie] School of Materials Science and Engineering, Central South University of Forestry and Technology, Changsha, Hunan 410004, China;[Jiali Chen; Chengling Wu; Ruijia Zhang] CAS Key Laboratory of Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Beijing 100190, China;Beijing Laboratory of Biomedical Materials, College of Materials Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, China;[Jie Zhao; Xiaobo Wu] School of Materials Science and Engineering, Central South University of Forestry and Technology, Changsha, Hunan 410004, China<&wdkj&>CAS Key Laboratory of Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Beijing 100190, China;[Qingxin Yao; Yuan Gao] CAS Key Laboratory of Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Beijing 100190, China<&wdkj&>Beijing Laboratory of Biomedical Materials, College of Materials Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, China
通讯机构：
[Jianjun Xie] S;School of Materials Science and Engineering, Central South University of Forestry and Technology, Changsha, Hunan 410004, China
关键词：
In situ supramolecular self-assembly;Nanomaterials;Enzyme;Multidrug resistance;Cancer
摘要：
Drug resistance is one of the major causes of cancer treatment failures. In recent years, to combat the issue of drug resistance, a large volume of strategies has been established along the development of biomedical nanomaterials. Compared with traditional nanocarrier-based drug delivery strategies, in situ supramolecular self-assembly has emerged as a promising strategy to overcome drug resistance. This review first introduced the concept of in situ supramolecular self-assembly. The second part illustrated the mechanisms of constructing in situ supramolecular self-assembly as a multi-step process. The third part elucidated the role of in situ supramolecular self-assembly to reverse drug resistance, which included three categories: active self-assembly materials, drug-carrier self-assembly materials and drug-coupled self-assembly materials. At last, we summarized the current development of in situ supramolecular self-assembly for the reversal of drug resistance and the remaining concerns to be addressed.
作者机构：
[吴小波; 谢建军; 赵婕] School of Materials Science and Engineering, Central South University of Forestry and Technology, Changsha 410004, Hunan, China;[高远; 吴小波; 赵婕; 姚庆鑫] CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety, National Center for Nanoscience and Technology, Beijing 100190, China;[姚庆鑫] School of Materials Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, China
作者机构：
[郝好; 谢建军] Central South University of Forestry and Technology, School of Materials Science and Engineering, Changsha;410004, China;[姚庆鑫; 高远] National Center for Nanoscience and Technology, CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety, Beijing;100190, China;[郝好] 410004, China<&wdkj&>National Center for Nanoscience and Technology, CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety, Beijing
作者机构：
[姚庆鑫; 谢建军; 赵玉双; 宋文淼; 成青] School of Materials Science and Engineering, Central South University of Forestry and Technology, Changsha;410004, China;[张平] School of Environmental Science and Engineering, Central South University of Forestry and Technology, Changsha;[姚庆鑫; 谢建军; 赵玉双; 宋文淼; 成青; 张平] 410004, China
通讯机构：
[Xie, J.] S;School of Materials Science and Engineering, China
作者机构：
[Qingxin Yao; Bei Wang; Hougui Yang; Jianjun Xie] School of Materials Science and Engineering,Central South University of Forestry and Technology
摘要：
The saponification hydrolysis of adsorbent composites comprising of bentonite/sodium lignosulfonate graft-polymerized with acrylamide and 2-acrylamido-2-methylpropanesulfonic acid(BLPAS) was investiga
作者机构：
[姚庆鑫; 阳后桂; 王蓓; 谢建军] School of Materials Science and Engineering, Central South University of Forestry and Technology, Changsha;410004, China;[姚庆鑫; 阳后桂; 王蓓; 谢建军] 410004, China
通讯机构：
[Xie, J.] S;School of Materials Science and Engineering, China
摘要：
为揭示外加电解质离子强度对重金属离子吸附的影响规律与内在机制,制备了膨润土/木质素磺酸钠接枝丙烯酰胺-马来酸酐复合吸附树脂(BLPAMA),研究了外加电解质离子强度对BLPAMA吸附单一和二元Pb~(2+)/Cu~(2+)的影响规律,以及有、无外加0.2 mol/L Na NO3时BLPAMA对二元Pb~(2+)/Cu~(2+)的吸附等温线、吸附热力学及吸附动力学。结果表明,在单一Pb~(2+)或Cu~(2+)溶液中,随离子强度增加,Pb~(2+)和Cu~(2+)吸附量降低;在二元Pb~(2+)/Cu~(2+)溶液中,随离子强度增加,Pb~(2+)吸附量降低而Cu~(2+)吸附量提高。
作者机构：
[姚庆鑫; 谢建军; 刘军霞; 唐丽萍] School of Materials Science and Engineering, Central South University of Forestry and Technology, Changsha, Hunan Province 410004, China
通讯机构：
School of Materials Science and Engineering, Central South University of Forestry and Technology, Changsha, Hunan Province, China
