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Effect of resveratrol on drug resistance in colon cancer chemotherapy

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成果类型:
期刊论文
作者:
Huang, Lu;Zhang, Sheng;Zhou, Jun;Li, Xiangzhou*
通讯作者:
Li, Xiangzhou
作者机构:
[Huang, Lu; Zhou, Jun; Zhang, Sheng; Li, Xiangzhou] Cent South Univ Forestry & Technol, Sch Mat Sci & Engn, 498 South Shaoshan Ave, Changsha 410004, Hunan, Peoples R China.
[Li, Xiangzhou] Natl Engn Lab Southern Forestry Ecol Applicat Tec, Changsha 410004, Hunan, Peoples R China.
通讯机构:
[Li, Xiangzhou] C
[Li, Xiangzhou] N
Cent South Univ Forestry & Technol, Sch Mat Sci & Engn, 498 South Shaoshan Ave, Changsha 410004, Hunan, Peoples R China.
Natl Engn Lab Southern Forestry Ecol Applicat Tec, Changsha 410004, Hunan, Peoples R China.
语种:
英文
期刊:
RSC Advances
ISSN:
2046-2069
年:
2019
卷:
9
期:
5
页码:
2572-2580
基金类别:
National Key R&D Program of China [2016YFD0600805]
机构署名:
本校为第一且通讯机构
院系归属:
材料科学与工程学院
摘要:
To investigate the effects of resveratrol on the drug resistance of 5-FU in the colon cancer chemotherapy, an MTT assay was used to detect the effects of 5-FU and resveratrol combined with 5-FU on the proliferation of the LoVo and SW480 cell lines. Flow cytometry was used to detect the effect of 5-FU combined with resveratrol on the survival rate of the LoVo and SW480 cells. A western blot was used to detect the expression levels of the proteins associated with colon cancer. After flow sorting, the percentage of the SW480 and the LoVo cell line...

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