期刊论文

Antibacterial mechanism of gastrointestinal biomimetic digestants from peanut peptide-ferrous on Staphylococcus aureus

中文

食品与发酵工业

0253-990X

2020

46

18

111-116

10.13995/j.cnki.11-1802/ts.024124

湖南省自然科学基金科教联合基金(2018JJ5022) 湖南省教育厅科研项目(18C1356)。

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为探讨花生肽亚铁胃肠仿生消化产物作为抑菌剂的潜在可能性,从抑菌活性、表面疏水性、最低抑菌浓度(minimum inhibitory concentration,MIC) 、细胞膜渗透性、紫外吸收大分子物质和K +泄漏等方面进行了研究。结果表明,胃肠仿生消化能增强花生肽亚铁抑菌活性;仿生消化270 min时表面疏水值最大;小肠仿生消化产物(simulated intestinal fragment,SIF4)为0.2 × 10 ~(- 3) g/L时(MIC)对金黄色葡萄球菌有明显抑菌作用;试验组细胞膜渗透性、蛋白质和核酸等紫外吸收物质泄露与对照组均有显著差异(P

To explore the potential of peanut peptide ferrous (PPF) gastrointestinal bionic digestants (GBDs) as an antibacterial agent,antibacterial activity (ABA),surface hydrophobicity (SHP), minimum inhibitory concentration (MIC),cell membrane permeability (CMP),the extracellular leakage of ultraviolet absorption biomacromolecules and K + were studied. The results showed that the ABA of PPF can be enhanced by gastrointestinal biomimetic digestive treatment. The SHP attained its'peak at 270 min. Simulated intestinal fragment (SIF4) at the concentration...