HAMdb: a database of human autophagy modulators with specific pathway and disease information

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Wang, Ning-Ning;Dong, Jie;Zhang, Lin;Ouyang, Defang;Cheng, Yan;...

通讯作者：

Cao, Dong-Sheng

作者机构：

[Cheng, Yan; Dong, Jie; Wang, Ning-Ning; Cao, Dong-Sheng] Cent S Univ, Xiangya Sch Pharmaceut Sci, 172 Tongzipo Rd, Changsha, Hunan, Peoples R China.

[Dong, Jie; Zhang, Lin] Cent South Univ Forestry & Technol, Hunan Key Lab Grain Oil Deep Proc & Qual Control, Hunan Key Lab Proc Food Special Med Purpose, Natl Engn Lab Deep Proc Rice & Byprod, Changsha, Hunan, Peoples R China.

[Ouyang, Defang] Univ Macau, State Key Lab Qual Res Chinese Med, Inst Chinese Med Sci, Macau, Peoples R China.

[Chen, Alex F.; Cao, Dong-Sheng] Cent S Univ, Ctr Vasc Dis & Translat Med, Xiangya Hosp 3, Changsha, Hunan, Peoples R China.

[Cao, Dong-Sheng; Lu, Ai-Ping] Hong Kong Baptist Univ, Inst Adv Translat Med Bone & Joint Dis, Sch Chinese Med, Hong Kong, Hong Kong, Peoples R China.

通讯机构：

[Cao, Dong-Sheng] C

[Cao, Dong-Sheng] H

Cent S Univ, Xiangya Sch Pharmaceut Sci, 172 Tongzipo Rd, Changsha, Hunan, Peoples R China.

Cent S Univ, Ctr Vasc Dis & Translat Med, Xiangya Hosp 3, Changsha, Hunan, Peoples R China.

Hong Kong Baptist Univ, Inst Adv Translat Med Bone & Joint Dis, Sch Chinese Med, Hong Kong, Hong Kong, Peoples R China.

语种：

英文

关键词：

Autophagy;Autophagy modulator;Database;Disease;Pathophysiological;Pathway

期刊：

Journal of Cheminformatics

ISSN：

1758-2946

年：

2018

卷：

期：

页码：

1-8

DOI：

10.1186/s13321-018-0289-4

基金类别：

This work is financially supported by the National Key Basic Research Program (2015CB910700), the National Natural Science Foundation of China (Grants No. 81402853, 81501619), program for Science &Technology Innovation Talents of Hunan Province (2017TP1021), and the Project of Innovation‑driven Plan in Central South University. The studies meet with the approval of the university’s review board.

机构署名：

本校为其他机构

院系归属：

食品科学与工程学院

摘要：

Autophagy is an important homeostatic cellular recycling mechanism responsible for degrading unnecessary or dysfunctional cellular organelles and proteins in all living cells. In addition to its vital homeostatic role, this degradation pathway also involves in various human disorders, including metabolic conditions, neurodegenerative diseases, cancers and infectious diseases. Therefore, the comprehensive understanding of autophagy process, autophagy-related modulators and corresponding pathway and disease information will be of great help for i...

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HAMdb: a database of human autophagy modulators with specific pathway and disease information

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