National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31201348/31571874]; Hunan Youth Excellent Talents Supporting Program [2016RS3033]; Natural Science Foundation of Hunan ProvinceNatural Science Foundation of Hunan Province [2017JJ2410]; Central South University of Forestry and Technology [2015JC03]; Grain-oil Process and Quality Control Collaborative and Innovative Grant from Hunan Province
机构署名:
本校为第一且通讯机构
院系归属:
食品科学与工程学院
摘要:
Reactive oxygen species-induced vessel endothelium injury is crucial in cardiovascular diseases progression. Rice-derived bran bioactive peptides (RBAP) might exert antioxidant effect through unknown mechanisms. Herein, we validated the antioxidant effect and mechanism of RBAP on H2O2-induced oxidative injury in human umbilical vein endothelial cells (HUVECs). Here, HUVECs were treated with RBAP under H2O2stimulation;the effects of RBAP on HUVECs oxidative injury were evaluated. H2O2injury-induced cell morphology changes were ameliorated by RBAP. The effect of H2O2- on HUVEC apoptosis (percent...