Construction of a super large Stokes shift near-infrared fluorescent probe for detection and imaging of superoxide anion in living cells, zebrafish and mice

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成果类型：

期刊论文

作者：

Zhao, Xiongjie*;Chen, Xinyi;Wu, You;Wang, Jing;Lin, Pengxu;...

通讯作者：

Zhao, Xiongjie;Wang, ZC

作者机构：

[Wang, Zongcheng; Chen, Xinyi; Zhao, Xiongjie; Zhao, XJ; Wu, You; Wang, Jing] Hunan Univ Sci & Engn, Coll Chem & Biol Engn, Yongzhou 425199, Hunan, Peoples R China.

[Zhou, Liyi; Lin, Pengxu] Cent South Univ Forestry & Technol, Coll Food Sci & Engn, Changsha 410004, Hunan, Peoples R China.

[Wang, Zongcheng; Chen, Xinyi; Zhao, Xiongjie; Zhao, XJ; Wu, You; Wang, Jing] Hunan Univ Sci & Engn, Hunan Engn Technol Res Ctr Comprehens Dev & Utiliz, Yongzhou 425199, Hunan, Peoples R China.

通讯机构：

[Wang, ZC ; Zhao, XJ] H

Hunan Univ Sci & Engn, Coll Chem & Biol Engn, Yongzhou 425199, Hunan, Peoples R China.

Hunan Univ Sci & Engn, Hunan Engn Technol Res Ctr Comprehens Dev & Utiliz, Yongzhou 425199, Hunan, Peoples R China.

语种：

英文

关键词：

Acute inflammation;Fluorescence imaging;Living cells;NIR fluorescent probe;Superoxide anion

期刊：

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

ISSN：

1386-1425

年：

2024

卷：

309

页码：

123806

DOI：

10.1016/j.saa.2023.123806

基金类别：

Natural Science of Foundation of Hunan Province of China [2021JJ40219]; Scientific Research Project of Education Department of Foundation of Hunan Province of China [22B0799]; Construct program of applied characteristic displine in Hunan Province

机构署名：

本校为其他机构

院系归属：

食品科学与工程学院

摘要：

As one of the major reactive oxygen species (ROS), superoxide anion (O-2(center dot-)) is engaged in maintaining redox homeostasis in the cell microenvironment. To identify the pathological roles in related disorders caused by abnormal expression of O-2(center dot-), it is of great significance to monitor and track the fluctuation of O-2(center dot-) concentration in vivo. However, the low concentration of O-2(center dot-) and the interference caused by tissue autofluorescence make the development of an ideal detection methodology full of challenges. Herein, a "Turn-On" chemical response near-...

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Construction of a super large Stokes shift near-infrared fluorescent probe for detection and imaging of superoxide anion in living cells, zebrafish and mice

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