Tannin was extracted from wild persimmon leaves (Diospyros kaki L.f ) using the ultrasonic-assisted semi-bionic approach. Infrared spectrum analysis showed that tannins from wild persimmon leaves contain many proanthocyanidin-like substances with 3-O-gallate acyl structure. Free radical scavenging capacity assay showed that the ultrasonic-assisted semi-bionic approach can improve the scavenging activity of tannins on radicals, including OH, DPPH and ABTS+. The half maximal inhibitory concentration values were reduced by 0.62, 0.116 and 1.19 mg ...