As a secondary oxidation product derived during rice bran oxidative rancidity, malondialdehyde (MDA) was selected to study the impact of oxidative rancidity on the digestion properties of rice bran protein. MDA modification promoted the content of protein carbonyl groups and disulfide bonds from 2.0 to 10.34 nmol/mg, 12.04–16.51 nmol/mg, respectively. The results of FT-IR, intrinsic fluorescence spectra, surface hydrophobicity, molecular weight distribution and protein electrophoresis implied that MDA changed the secondary structure of rice br...