Whole grain germinated brown rice intake modulates the gut microbiota and alleviates hypertriglyceridemia and hypercholesterolemia in high fat diet-fed mice

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成果类型：

期刊论文

作者：

Han, Shuai;Wu, Xiuxiu;Zhu, Lingfeng;Lu, Han;Ling, Xuke;...

通讯作者：

Luo, FJ

作者机构：

[Wu, Xiuxiu; Zhou, Yaping; Luo, Feijun; Lu, Han; Ling, Xuke; Luo, FJ; Han, Shuai; Hu, Zuomin; Zhu, Lingfeng] Cent South Univ Forestry & Technol, Coll Food Sci & Engn, Lab Mol Nutr, 498 Southern Shaoshan Rd, Changsha 410004, Hunan, Peoples R China.

[Luo, Yi] Cent South Univ, Xiangya Sch Med, Dept Clin Med, Changsha 410008, Hunan, Peoples R China.

[Luo, Feijun; Tang, Yiping; Luo, FJ] Natl Engn Res Ctr Rice & Byproduct Deep Proc, 498 South Shaoshan Rd, Changsha 410004, Hunan, Peoples R China.

通讯机构：

[Luo, FJ ] C

Cent South Univ Forestry & Technol, Coll Food Sci & Engn, Lab Mol Nutr, 498 Southern Shaoshan Rd, Changsha 410004, Hunan, Peoples R China.

Natl Engn Res Ctr Rice & Byproduct Deep Proc, 498 South Shaoshan Rd, Changsha 410004, Hunan, Peoples R China.

语种：

英文

期刊：

FOOD & FUNCTION

ISSN：

2042-6496

年：

2024

卷：

期：

页码：

265-283

DOI：

10.1039/d3fo03288d

基金类别：

Central South University of Forestry and Technology [2022YFF1100200]; Key Projects of the State Key R&D Program, China [CX20210862]; Post-graduate Scientific Research Innovations Project of Hunan Province [CX202101027]; Scientific Innovation Fund for Post-graduates of the Central South University of Forestry and Technology

机构署名：

本校为第一且通讯机构

院系归属：

食品科学与工程学院

摘要：

Hyperlipidemia is a common clinical disorder of lipid metabolism in modern society and is considered to be one of the major risk factors leading to cardiovascular-related diseases. Germinated brown rice (GBR) is a typical whole grain food. The lipid-lowering effect of GBR has received increasing attention, but its mechanism of action is not fully understood. The gut microbiota has been proposed as a novel target for the treatment of hyperlipidemia. The aim of this study was to investigate the effects of GBR on the gut microbiota and lipid metabolism in high-fat diet (HFD)-fed C57BL/6J mice. Th...

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Whole grain germinated brown rice intake modulates the gut microbiota and alleviates hypertriglyceridemia and hypercholesterolemia in high fat diet-fed mice

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