Threaded 3D microfluidic paper analytical device-based ratiometric fluorescent sensor for background-free and visual detection of organophosphorus pesticides

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成果类型：

期刊论文

作者：

Tong, Xia;Cai, Guihan;Xie, Lianwu*;Wang, Tongtao;Zhu, Yongfeng;...

通讯作者：

Xie, Lianwu;Shi, SY;Guo, Y

作者机构：

[Shi, SY; Shi, Shuyun; Xie, Lianwu; Peng, Yuqing; Tong, Xia] Cent South Univ Forestry & Technol, Coll Sci, Changsha 410004, Hunan, Peoples R China.

[Shi, Shuyun; Wang, Tongtao; Zhu, Yongfeng; Tong, Chaoying; Tong, Xia; Cai, Guihan] Cent South Univ, Coll Chem & Chem Engn, Changsha 410083, Hunan, Peoples R China.

[Tong, Xia] Shanxi Med Univ, Shanxi Acad Med Sci, Hosp 3, Shanxi Bethune Hosp, Taiyuan 030032, Shanxi, Peoples R China.

[Guo, Ying; Guo, Y] Cent South Univ, Xiangya Hosp, Dept Clin Pharmacol, Hunan Key Lab Pharmacogenet, Changsha 410078, Hunan, Peoples R China.

通讯机构：

[Shi, SY ; Xie, LW; Guo, Y ] C

Cent South Univ Forestry & Technol, Coll Sci, Changsha 410004, Hunan, Peoples R China.

Cent South Univ, Xiangya Hosp, Dept Clin Pharmacol, Hunan Key Lab Pharmacogenet, Changsha 410078, Hunan, Peoples R China.

语种：

英文

关键词：

Background-free analysis;Organophosphorus pesticide;Ratiometric fluorescent system;Threaded 3D microfluidic paper device;Visual detection

期刊：

Biosensors and Bioelectronics

ISSN：

0956-5663

年：

2023

卷：

222

页码：

114981

DOI：

10.1016/j.bios.2022.114981

基金类别：

CRediT authorship contribution statement Xia Tong: Methodology, Data curation, Writing – original draft. Guihan Cai: Formal analysis, Investigation. Lianwu Xie: Methodology, Resources, Writing – review & editing. Tongtao Wang: Validation, Visualization. Yongfeng Zhu: Data curation, Investigation. Yuqing Peng: Validation, Data curation. Chaoying Tong: Investigation. Shuyun Shi: Writing – review & editing, Supervision, acquisition. Ying Guo: Methodology, Project administration, Conceptualization.

机构署名：

本校为第一且通讯机构

院系归属：

理学院

摘要：

With the increasing concerns of food safety and environmental protection, it is desirable to develop reliable, effective, and portable sensors for detection of organophosphorus pesticides (OPs). Here, a cascade reaction system integrated with threaded 3D microfluidic paper analytical device (3D μPAD) was firstly developed for background-free and visual detection of OPs in agricultural samples. Butyrylcholinesterase (BChE) hydrolyzed acetylcholine into thiocholine (TCh), which reduced MnO(2) nanosheets into Mn(2+). With addition of OPs, BChE ac...

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