New meroterpenoid compounds from the culture of mushroom Panus lecomtei

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成果类型：

期刊论文

作者：

Wang Si-Xian;Zhao Rui-Lin;Guo Cui;Chen Bao-Song;Dai Huan-Qin;...

通讯作者：

Liu Gao-Qiang;Liu Hong-Wei

作者机构：

[Wang Si-Xian; Liu Gao-Qiang] Cent South Univ Forestry & Technol, Hunan Prov Key Lab Forestry Biotechnol, Changsha 410004, Peoples R China.

[Wang Si-Xian; Liu Gao-Qiang] Cent South Univ Forestry & Technol, Int Cooperat Base Sci & Technol Innovat Forest Re, Changsha 410004, Peoples R China.

[Wang Si-Xian; Liu Hong-Wei; Zhao Rui-Lin; Guo Cui; Chen Bao-Song; Dai Huan-Qin] Chinese Acad Sci, Inst Microbiol, State Key Lab Mycol, Beijing 100101, Peoples R China.

[Liu Hong-Wei; Zhao Rui-Lin; Guo Cui; Chen Bao-Song; Dai Huan-Qin] Univ Chinese Acad Sci, Savaid Med Sch, Beijing 100049, Peoples R China.

通讯机构：

[Liu Gao-Qiang; Liu Hong-Wei] C

[Liu Hong-Wei] U

Cent South Univ Forestry & Technol, Hunan Prov Key Lab Forestry Biotechnol, Changsha 410004, Peoples R China.

Cent South Univ Forestry & Technol, Int Cooperat Base Sci & Technol Innovat Forest Re, Changsha 410004, Peoples R China.

Chinese Acad Sci, Inst Microbiol, State Key Lab Mycol, Beijing 100101, Peoples R China.

语种：

英文

关键词：

Panus lecomtei;Meroterpenoid;Antibacterial;Biosynthetic pathway

期刊：

中国天然药物

ISSN：

2095-6975

年：

2020

卷：

期：

页码：

268-272

DOI：

10.1016/S1875-5364(20)30033-9

基金类别：

[Received on] 23-Dec.-2019 [Research funding] This work was supported by National Key R&D Program of China (Nos. 2018YFD0400203, 2017YFE0108200 and 2017YFE0108100), the National Natural Science Foundation of China (Nos. 81673334 and 31772374). [*Corresponding author] E-mail:gaoliuedu@csuft.edu.cn (LIUGao-Qiang) ; liuhw@im.ac.cn ( LIU Hong-Wei ) ∆These authors contributed equally to this work. These authors have no conflict of interest to declare.

机构署名：

本校为第一且通讯机构

院系归属：

生命科学与技术学院

摘要：

Two new meroterpenoid compounds (1 and 2) together with five known meroterpenoid derivatives (3–7) were isolated from solid culture of mushroom Panus lecomtei. The structures of new compounds were confirmed by the analysis of NMR and HR-ESI-MS spectroscopic data. The biosynthetic pathway of 1–7 was postulated. All isolated compounds were evaluated for antibacterial activities against Staphylococcus aureus, Escherichia coli, Bacillus subtilis, Pseudomonas aeruginosa and Bacillus Calmette–Guérin. Compound 3 exhibited weak antibacterial activi...

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New meroterpenoid compounds from the culture of mushroom Panus lecomtei

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