Toward improvements for carrying capacity of the cyclodextrin-based nanosponges: recent progress from a material and drug delivery

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成果类型：

期刊论文

作者：

Deng, Jing;Chen, Qi Jue;Li, Wen*;Zuberi, Zavuga;Feng, Jian Xiang;...

通讯作者：

Li, Wen

作者机构：

[Lin, Qin Lu; Deng, Jing; Li, Wen; Ren, Jia Li; Luo, Fei Jun] Cent South Univ Forestry & Technol, Natl Engn Lab Deep Proc Rice & Byprod, Hunan Prov Key Lab Edible Forestry Resources Safe, Coll Food Sci & Engn,Hunan Key Lab Processed Food, Changsha 410004, Hunan, Peoples R China.

[Zeng, Xiao Xi; Ma, Liang; Deng, Jing; Chen, Qi Jue; Feng, Jian Xiang; Zheng, Xiang Min; Li, Wen; Ding, Quan Ming] Hunan Univ Technol, Coll Life Sci & Chem, Coll Packaging & Mat Engn, Zhuzhou 412007, Hunan, Peoples R China.

[Zuberi, Zavuga] Dar Es Salaam Inst Technol, Dept Sci & Lab Technol, POB 2958, Dar Es Salaam, Tanzania.

[Yin, Hua Qun] Cent South Univ, Sch Resource Proc & Bioengn, Changsha 410083, Hunan, Peoples R China.

通讯机构：

[Li, Wen] C

[Li, Wen] H

Cent South Univ Forestry & Technol, Natl Engn Lab Deep Proc Rice & Byprod, Hunan Prov Key Lab Edible Forestry Resources Safe, Coll Food Sci & Engn,Hunan Key Lab Processed Food, Changsha 410004, Hunan, Peoples R China.

Hunan Univ Technol, Coll Life Sci & Chem, Coll Packaging & Mat Engn, Zhuzhou 412007, Hunan, Peoples R China.

语种：

英文

关键词：

Cyclodextrins;Molecules;Targeted drug delivery;Cyclodextrin cavities;Drug encapsulation;Hydrophilic and hydrophobic;Multifunctional properties;Natural materials;Pharmaceutical industry;Recent progress;Small molecules;Controlled drug delivery

期刊：

Journal of Materials Science

ISSN：

0022-2461

年：

2021

卷：

期：

页码：

5995-6015

DOI：

10.1007/s10853-020-05646-8

基金类别：

This study was funded by the National Key R&D Program of China (2018YFE0110200), the Natural Science Foundation of Hunan Province of China (2020JJ4278, 2020JJ5127, and 2018JJ4061), the key program of Hunan Provincial Department of science and technology (2020WK2020 and 2019NK2111), Program for Science & Technology Innovation Platform/Talents of Hunan Province (2019TP1029), the Scientific Research Fund of Hunan Provincial Education Department (18B290), and Zhuzhou Key Science & Technology Program of Hunan Province (2017, 2018, and 2019).

机构署名：

本校为第一且通讯机构

院系归属：

食品科学与工程学院

摘要：

Abstract: Cyclodextrins are a type of natural materials that can be used in the pharmaceutical industry. Cyclodextrins are safe, biodegradable, with the multifunctional property as they can encapsulate both hydrophilic and hydrophobic drugs. Additionally, they can overcome challenges associated with drug toxicity and enhancing the solubility of the insoluble drugs; thus, cyclodextrins are effective carriers in loading tiny molecules. Moreover, the synthesis of nanosponges (NPs) systems can enhance the drug encapsulation in cyclodextrin cavities...

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Toward improvements for carrying capacity of the cyclodextrin-based nanosponges: recent progress from a material and drug delivery

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