Research Progress on Signaling Pathway-Associated Oxidative Stress in Endothelial Cells

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成果类型：

期刊论文

作者：

Liang, Ying;Li, Jiajia;Lin, Qinlu*;Huang, Ping;Zhang, Lin;...

通讯作者：

Lin, Qinlu

作者机构：

[Huang, Ping; Li, Jiajia; Wu, Wei; Ma, Youchu; Zhang, Lin; Liang, Ying; Lin, Qinlu] Cent South Univ Forestry & Technol, Natl Engn Lab Rice & Byprod Deep Proc, Changsha 410004, Hunan, Peoples R China.

[Huang, Ping; Li, Jiajia; Wu, Wei; Ma, Youchu; Zhang, Lin; Liang, Ying; Lin, Qinlu] Cent South Univ Forestry & Technol, Coll Food Sci & Engn, Changsha 410004, Hunan, Peoples R China.

通讯机构：

[Lin, Qinlu] C

Cent South Univ Forestry & Technol, Natl Engn Lab Rice & Byprod Deep Proc, Changsha 410004, Hunan, Peoples R China.

Cent South Univ Forestry & Technol, Coll Food Sci & Engn, Changsha 410004, Hunan, Peoples R China.

语种：

英文

关键词：

Cell signaling;Cells;Cytology;Diseases;Oxidative stress;Cardio-vascular disease;Scientific direction;Signal pathways;Signaling pathways;Endothelial cells;eNOS protein;hydroxymethylglutaryl coenzyme A reductase kinase;immunoglobulin enhancer binding protein;PI3K protein;protein;protein kinase B;unclassified drug;cell function;cell growth;endothelium cell;human;oxidation;oxidative stress;Review;signal transduction;animal;biological model;endothelium cell;metabolism;oxidation reduction reaction;pathology;Cells;Medicine;Animals;Endothelial Cells;Humans;Models, Biological;Oxidation-Reduction;Oxidative Stress;Signal Transduction

期刊：

Oxidative Medicine and Cellular Longevity

ISSN：

1942-0900

年：

2017

卷：

2017

页码：

7156941

DOI：

10.1155/2017/7156941

基金类别：

This work was supported by funding from the National Natural Science Foundation of China (no. 31201348/31571874), Hunan Youth Excellent Talents Supporting Program (no. 2016RS3033), Construction Project of Graduate textbook from Central South University of Forestry and Technology (no. 2015JC03), the Natural Science Foundation of Hunan Province (no. 2017JJ2410), Grain-oil Process and Quality Control 2011 Collaborative and Innovative grant from Hunan province.

机构署名：

本校为第一且通讯机构

院系归属：

食品科学与工程学院

摘要：

Studying the mechanisms of oxidative stress in endothelial cells is vital to the discovery of novel drugs for the treatment of cardiovascular disease. This article reviews the progress within the field of the role of oxidative responses in the physiology and growth of endothelial cells and emphasizes the effects of several main signal pathways involved in the oxidative stress of endothelial cells. Herein, we aim to provide scientific direction that can serve as a basis for researchers specializing in the sign...

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