期刊论文

Research Progress for Genetic Modification of Butanol-producing Clostridia

中文

生物技术通报

1002-5464

2017

33

1

106-113

10.13560/j.cnki.biotech.bull.1985.2017.01.011

2011-4-13:引进国际先进林业科学技术项目项目)

本校为第一机构

产丁醇梭菌作为丁醇发酵的主要生产菌,近年来成为研究的热点,而丁醇作为新型可再生能源,其优势远大于乙醇,因此,对产丁醇梭菌的基因改造研究具有重大意义。从关键基因、糖酵解途径和丁醇耐受性的角度出发,介绍了近几年来对产丁醇梭菌基因改造的研究进展。讨论了目前研究存在的问题,并对如何提高丁醇产量提出一些见解,旨为广大研究者提供新的思路。

Butanol-producing Clostridia as butanol fermentation strains have been studied frequently in recent years. As a new renewable energy sources,butanol has obviously more advantages than ethanol. Therefore,it is of great significance to study gene modification of butanol-producing Clostridia. In this review,from three aspects of key genes,glycolytic pathway,and butanol tolerance,we introduced the latest research progress on gene modification of butanol-producing Clostridia. Meanwhile,we discussed the issues in the current research,and put forward suggestions on how to improve the butanol yield,ai...