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成果类型:
期刊论文
作者:
Xiang, Yinping;Jia, Meiying;Xu, Rui;Xu, Jialu;He, Lele;...
通讯作者:
Xiong, WP
作者机构:
[Yang, Zhaohui; He, Lele; Xu, Jialu; Wang, Dongbo; Xiang, Yinping; Peng, Haihao; Xiong, Weiping] Hunan Univ, Coll Environm Sci & Engn, Changsha 410082, Peoples R China.
[Yang, Zhaohui; He, Lele; Xu, Jialu; Wang, Dongbo; Xiang, Yinping; Peng, Haihao; Xiong, Weiping] Hunan Univ, Key Lab Environm Biol & Pollut Control, Minist Educ, Changsha 410082, Peoples R China.
[Jia, Meiying] Cent South Univ Forestry & Technol, Coll Environm Sci & Engn, Changsha 410004, Peoples R China.
[Xu, Rui] Cent South Univ, Inst Environm Engn, Sch Met & Environm, Changsha 410083, Peoples R China.
[Sun, Weimin] Guangdong Acad Sci, Inst Ecoenvironm & Soil Sci, 808 Tianyuan Rd, Guangzhou 510650, Peoples R China.
通讯机构:
[Xiong, WP ] H
Hunan Univ, Coll Environm Sci & Engn, 1 Lushan South Rd, Changsha 410082, Peoples R China.
语种:
英文
关键词:
Anaerobic digestion;Antimicrobial resistance;Human pathogens;Metagenomic binning;Non-antibiotic pharmaceutical
期刊:
Bioresource Technology
ISSN:
0960-8524
年:
2024
卷:
391
期:
Pt A
页码:
129983
基金类别:
Acknowledgement The work was financially supported by the National Natural Science Foundation of China (52379064), the National Youth Foundation of China (52000064, 42007357), Hunan Provincial Natural Science Foundation of China (2023JJ0013), Special for the Construction of Hunan's Innovative Province (2021SK2040), the Science and Technology Innovation Program of Hunan Province (2021RC3133), the Hunan Municipal Natural Science Foundation (2023JJ41048).
机构署名:
本校为其他机构
院系归属:
环境科学与工程学院
摘要:
Antimicrobial resistance is a global health security issue of widespread concern. Recent studies have unveiled the potential contribution of non-antibiotics to the emergence of antimicrobial resistance. This study investigated the effect of carbamazepine, a non-antibiotic pharmaceutical, on the fate of antibiotic resistance genes (ARGs) during anaerobic digestion. The results, as revealed by both metagenomic sequencing and absolute quantification, demonstrated that carbamazepine induced the enrichment of ARGs and increased the abundance of ARGs hosts by 1.2-2.1 times. Carbamazepine facilitated...

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