Population genomics of wild Chinese rhesus macaques reveals a dynamic demographic history and local adaptation, with implications for biomedical research

认领

导出

下载 Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Liu, Zhijin;Tan, Xinxin;Orozco-terWengel, Pablo;Zhou, Xuming;Zhang, Liye;...

通讯作者：

Bruford, Michael W.;Li, Ming

作者机构：

[Li, Ming; Zhang, Liye; Liu, Zhijin; Yan, Zhongze; Tan, Xinxin; Ren, Baoping; Zhou, Xuming] Chinese Acad Sci, Inst Zool, Key Lab Anim Ecol & Conservat Biol, Beichen West Rd, Beijing 100101, Peoples R China.

[Zhang, Liye; Tan, Xinxin] Univ Chinese Acad Sci, Yuquan Rd, Beijing 100049, Peoples R China.

[Bruford, Michael W.; Orozco-terWengel, Pablo] Cardiff Univ, Sch Biosci, Sir Martin Evans Bldg,Museum Ave, Cardiff CF10 3AX, S Glam, Wales.

[Zhou, Xuming] Harvard Med Sch, Brigham & Womens Hosp, Dept Med, Div Genet, Boston, MA 02115 USA.

[Tian, Shilin] Novogene Bioinformat Inst, Jiuxianqiao North Rd, Beijing 100083, Peoples R China.

通讯机构：

[Bruford, Michael W.] C

[Li, Ming] I

Cardiff Univ, Sch Biosci, Sir Martin Evans Bldg,Museum Ave, Cardiff CF10 3AX, S Glam, Wales.

Inst Zool, CAS Key Lab Anim Ecol & Conservat Biol, Beichen West Rd, Beijing 100101, Peoples R China.

语种：

英文

关键词：

Adaptive selection;Biomedical model;Macaca mulatta;Population genomics

期刊：

GigaScience

ISSN：

2047-217X

年：

2018

卷：

期：

DOI：

10.1093/gigascience/giy106

基金类别：

This project was sponsored by grants to the following: M.L. (National Natural Science Foundation of China, 31530068 and 31821001; Strategic Priority Research Program of the Chinese Academy of Sciences, XDB31000000 and XDA19050202; National Key R&D Program of China, 2016YFC0503200; and Science & Technology Department of Sichuan Province, 2018JZ0008); Z.L. (Natural Science Foundation of China, 31471989).

机构署名：

本校为其他机构

院系归属：

生命科学与技术学院

摘要：

Background: The rhesus macaque (RM, Macaca mulatta) is the most important nonhuman primate model in biomedical research.We present the first genomic survey of wild RMs, sequencing 81 geo-referenced individuals of five subspecies from 17 locations in China, a large fraction of the species' natural distribution. Results: Populations were structured into five genetic lineages on the mainland and Hainan Island, recapitulating current subspecies designations. These subspecies are estimated to have diverged 125.8 to 51.3 thousand years ago, but featu...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Population genomics of wild Chinese rhesus macaques reveals a dynamic demographic history and local adaptation, with implications for biomedical research

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问