期刊论文

Design,synthesis and biological evalulation of novel mesoionic amide compounds

中文

农药

1006-0413

2023

62

06

391-395

10.16820/j.nyzz.2023.4010

湖南省重点研发计划项目(2020NK2019)。

本校为第一机构

[目的]为了发现结构新颖的高效杀虫剂。[方法]利用活性亚结构拼接法合成了一系列介离子类酰胺化合物，其结构经过1H NMR和HRMS确证。[结果]合成了15个结构新颖的介离子类酰胺化合物。生物活性测试结果表明：所合成的化合物对刺吸式害虫苜蓿蚜和朱砂叶螨没有生物活性，但部分化合物对咀嚼式口器害虫小菜蛾和黏虫具有一定活性。特别是化合物2a和2g在100 mg/L时对黏虫致死率为100%，且对小菜蛾致死率能达到80%及以上。[结论]合成的介离子类酰胺化合物具有一定的杀虫活性，为进一步研究提供了参考。

[Aims]To discover novel insecticide with improved activity.[Methods]A series of mesoionic amide compounds were synthesized on principle of biologically active factor splicing.Their structures were identified and confirmed by'H NMR and HRMS.[Results]15 New mesoionic ...MORE [Aims]To discover novel insecticide with improved activity.[Methods]A series of mesoionic amide compounds were synthesized on principle of biologically active factor splicing.Their structures were identified and confirmed by'H NMR and HRMS.[Results]15 New mesoionic amide compounds were synthesized.The results of biological a...