A holocellulose framework (HCFW) with anisotropic microchannels, which is synthesized via a facile top–down strategy, is demonstrated to be an ideal anisotropic substrate to guide the directional assembly of CuS nanoparticles (CuS NPs) along the walls of microchannels. The oxygen-containing groups on the surface of HCFW and its abundant low tortuosity of channels contribute to the high loading (ca. 22.7 wt%) and homogeneous dispersion of CuS NPs as well as the fast outdiffusion of cytotoxic substances (such as Cu(I)/Cu(II)), hence endowing the...
