Rhizosphere soil samples were collected from plants Nerium indicum, which grew well in a pot experiment with lead and zinc slag as substrates. The bacterial strains resistant to lead and zinc were isolated and identified, and the factors influencing lead and zinc adsorption and the adsorption mechanism were discussed. The results showed that: (1) Three bacterial strains (B1, B4, B14) could grow on the beef extract peptone medium that concentrated Pb2+ and Zn2+(600 mg · L-1). Based on morphology and molecular biology, B1, B4, and B14 were ident...