Simultaneous and early detection of Mycobacterium tuberculosis resistance to antituberculosis drugs using an indirect series piezoelectric system

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成果类型：

期刊论文

作者：

Ren, Jiali*;Ma, Lina;Li, Zhonghai;Lin, Qinlu;Huang, Hongxu;...

通讯作者：

Ren, Jiali

作者机构：

[Li, Zhonghai; Ren, Jiali; Ma, Lina; Lin, Qinlu] Cent South Univ Forestry & Technol, Coll Food Sci & Engn, Changsha 410004, Hunan, Peoples R China.

[Li, Zhonghai; Ren, Jiali; Ma, Lina; Lin, Qinlu] Natl Engn Lab Rice & By Prod Proc, Changsha 410004, Hunan, Peoples R China.

[Ren, Jiali] Hunan Univ, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China.

[Huang, Hongxu] Cent South Univ Forestry Technol, Coll Comp Sci & Informat Technol, Changsha 410004, Hunan, Peoples R China.

[Yi, Songlin] Hunan Inst TB Control, Changsha 410006, Hunan, Peoples R China.

通讯机构：

[Ren, Jiali] C

Cent South Univ Forestry & Technol, Coll Food Sci & Engn, Changsha 410004, Hunan, Peoples R China.

语种：

英文

关键词：

Drug resistance;Frequency shift profiles;ISP system;M. tuberculosis;QDT

期刊：

Biosensors and Bioelectronics

ISSN：

0956-5663

年：

2013

卷：

期：

页码：

115-119

DOI：

10.1016/j.bios.2012.12.009

基金类别：

Fig. 2(a) shows the real-time frequency shift responsive profiles with the initial M. tuberculosis H37Rv (ATCC 27294 ) concentrations ranging from 102 to 108 cfu/ml. No obvious frequency shift change was obtained while using the blank culture as the control, indicating the stability of the system. In the presence of M. tuberculosis H37Rv, the frequency shift decreases significantly following a small decrease. The response profile reflects the course of bacteria growth. The small decrease in

机构署名：

本校为第一且通讯机构

院系归属：

食品科学与工程学院

计算机与信息工程学院

摘要：

Emergence of drug-resistance tuberculosis (DR-TB) represents a serious threat to the world. Most countries, especially the developing countries, lack efficacious and inexpensive tools for early detection of Mycobacterium tuberculosis (M. tuberculosis) resistance to antituberculosis drugs and for preventing the carriers from acquiring further resistance. This report describes an indirect series piezoelectric (ISP) system for simultaneous and early detection of M. tuberculosis resistance to antituberculosis drugs. The ISP system can continually m...

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Simultaneous and early detection of Mycobacterium tuberculosis resistance to antituberculosis drugs using an indirect series piezoelectric system

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