TP-FRET-Based Fluorescent Sensor for Ratiometric Detection of Formaldehyde in Real Food Samples, Living Cells, Tissues, and Zebrafish

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成果类型：

期刊论文

作者：

Ding, Haiyuan;Yuan, Gangqiang;Peng, Longpeng;Zhou, Liyi*;Lin, Qinlu

通讯作者：

Zhou, Liyi

作者机构：

[Yuan, Gangqiang; Zhou, Liyi; Peng, Longpeng; Ding, Haiyuan; Lin, Qinlu] Cent South Univ Forestry & Technol, Hunan Key Lab Grain Oil Drip Proms & Qual Control, Natl Engn Lab Deep Proc Rice & Byprod,Coll Food S, Hunan Key Lab Processed Food Special Med Purpose, Changsha 410004, Hunan, Peoples R China.

通讯机构：

[Zhou, Liyi] C

Cent South Univ Forestry & Technol, Hunan Key Lab Grain Oil Drip Proms & Qual Control, Natl Engn Lab Deep Proc Rice & Byprod,Coll Food S, Hunan Key Lab Processed Food Special Med Purpose, Changsha 410004, Hunan, Peoples R China.

语种：

英文

关键词：

Energy transfer;Formaldehyde;Histology;Photons;Probes;Tissue;Fluorescence resonance energy transfer;Fluorescent probes;highly reactive carbonyl species;Pathological functions;Push-pull structures;Ratiometric detection;Ratiometric imaging;Zebrafish;Forster resonance energy transfer;fluorescent dye;formaldehyde;animal;fluorescence resonance energy transfer;HeLa cell line;human;zebra fish;Animals;Fluorescence Resonance Energy Transfer;Fluorescent Dyes;Formaldehyde;HeLa Cells;Humans;Zebrafish

期刊：

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

ISSN：

0021-8561

年：

2020

卷：

期：

页码：

3670-3677

DOI：

10.1021/acs.jafc.9b08114

基金类别：

This work was supported by Natural Science Foundation of China (NSFC, Grants 21605046), Hunan Provincial Natural Science Foundation of China (no. 2017JJ3060), Changsha Science and Technology Bureau Fund Project (no. kq1901140), and Science and Technology Innovation Platform and Talent Project of Hunan Province (2017TP1021).

机构署名：

本校为第一且通讯机构

院系归属：

食品科学与工程学院

摘要：

Formaldehyde (FA, HCHO) is a highly reactive carbonyl species, which is very harmful to humans and the environment as a tissue fixative and preservative. Therefore, developing some highly sensitive, selective, and rapid detection methods is significant for human health in food safety and environmental protection. Herein, a two-photon (TP) ratiometric sensor, CmNp-CHO, has been constructed by conjugating a TP donor (Î -push-pull-structure) with a FA off-on acceptor (functioned with hydrazide moiety) via a nonconjugated linker through the fluore...

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TP-FRET-Based Fluorescent Sensor for Ratiometric Detection of Formaldehyde in Real Food Samples, Living Cells, Tissues, and Zebrafish

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