期刊论文

Research progress on cardiovascular protective effects of tocotrienol

中文

生命的化学

1000-1336

2019

39

5

1013-1018

10.13488/j.smhx.20190043

2018湖南省自然科学基金(2018JJ2672) 湖南省教育厅科研项目(15C0890).

本校为第一机构

心血管疾病是全球主要的病死原因,对其进行防治具有重要的意义。生育三烯酚是维生素E的主要成分之一,具有抗氧化、降胆固醇、抗炎和抗肿瘤等多种生物学活性。近年来,大量研究表明,生育三烯酚在抗动脉粥样硬化、改善心肌缺血后再灌注损伤、降血压、抑制心血管炎症等方面具有较好的效果。本文针对近年来生育三烯酚对心血管疾病的防治研究进行综述,概述了生育三烯酚对心血管疾病的保护作用及其分子机理,旨在为生育三烯酚在心血管疾病防治方面的应用提供参考。

Cardiovascular diseases (CDV) are the main causes of death in the world and they are of great significance for their prevention and treatment. Tocotrienol is one of the main components of vitamin E, which has many biological activities, such as antioxidant, cholesterol-lowering, anti-inflammation and anti-cancer. In recent years, a large number of studies indicated that tocotrienol has good effects in the prevention and treatment of cardiovascular diseases, such as anti-atherosclerosis, improving myocardial ischemia reperfusion injury, lowering blood pressure, and inhibiting cardiovascular inf...