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Applications of a fluorescent nanoprobe-based visual tool using selenium nanoparticles on cadmium-induced liver fibrosis

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成果类型:
期刊论文
作者:
Jiang, Shali;Ran, Hongyan;Luo, Kun;Xu, Ping;Peng, Yongbo;...
通讯作者:
Zhou, LY;Peng, YB
作者机构:
[Jiang, Shali; Luo, Kun; Zhou, Liyi] Cent South Univ Forestry & Technol, Coll Food Sci & Engn, Changsha 410004, Hunan, Peoples R China.
[Peng, Yongbo; Ran, Hongyan; Xu, Ping] Chongqing Med Univ, Coll Pharm, Key Lab Biochem & Mol Pharmacol, Chongqing Key Lab Pharmaceut Metab Res, Chongqing 400016, Peoples R China.
通讯机构:
[Peng, YB ; Zhou, LY ] C
Cent South Univ Forestry & Technol, Coll Food Sci & Engn, Changsha 410004, Hunan, Peoples R China.
Chongqing Med Univ, Coll Pharm, Key Lab Biochem & Mol Pharmacol, Chongqing Key Lab Pharmaceut Metab Res, Chongqing 400016, Peoples R China.
语种:
英文
关键词:
Liver fibrosis;Cadmium;Nano-selenium;Fluorescent nanoprobe
期刊:
Sensors and Actuators B-Chemical
ISSN:
0925-4005
年:
2025
卷:
443
页码:
138293
基金类别:
CRediT authorship contribution statement Ping Xu: Formal analysis, Data curation. Liyi Zhou: Writing – review & editing, acquisition, Conceptualization. Yongbo Peng: Writing – review & editing, Supervision, acquisition. Shali Jiang: Writing – original draft, Investigation, Formal analysis, Data curation. Kun Luo: Investigation, Formal analysis, Data curation. Hongyan Ran: Investigation, Formal analysis, Data curation.
机构署名:
本校为第一且通讯机构
院系归属:
食品科学与工程学院
摘要:
Cadmium (Cd) is a non-essential heavy metal that enters the body through the food chain, accumulating in various organs, especially in the liver, where it can cause liver fibrosis. Selenium (Se), an essential trace element, can inhibit heavy metal toxicity by affecting antioxidant and chelating properties. Also, Se mainly exists as selenocysteine (Sec) in humans. In addition, there are some shortcomings in the current diagnosis of liver fibrosis. Therefore, there is an urgent need to develop a visualization tool to study and assess the antagonistic effects of selenium and cadmium in a mouse li...

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