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A sequential dual-locked luminescent copper nanocluster probe for tumor cell imaging and killing

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成果类型:
期刊论文
作者:
Chen, Fei;Xie, Ling;Deng, Ting;Li, Jishan
通讯作者:
Li, JS;Deng, T
作者机构:
[Chen, Fei; Li, Jishan; Xie, Ling] Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Peoples R China.
[Deng, Ting] Cent South Univ Forestry & Technol, Sch Sci, Inst Appl Chem, Changsha 410004, Hunan, Peoples R China.
通讯机构:
[Deng, T ] C
[Li, JS ] H
Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Peoples R China.
Cent South Univ Forestry & Technol, Sch Sci, Inst Appl Chem, Changsha 410004, Hunan, Peoples R China.
语种:
英文
关键词:
Dual-locked luminescence nanoprobe;Copper nanoclusters (CuNCs);Specific imaging of tumor cells;Fenton reaction;Therapy
期刊:
Microchimica Acta
ISSN:
0026-3672
年:
2024
卷:
191
期:
9
页码:
1-10
基金类别:
This work was financially supported by the National Natural Science Foundation of China (22376224, 22274039).
机构署名:
本校为通讯机构
院系归属:
理学院
摘要:
Asequential dual-locked luminescent copper nanoclusters (CuNCs) probe was designed and synthesizedfor the specific imaging and selective killing of tumor cells. This nanoprobe was prepared by first forming a Fe(3+)-coupled tannic acid (TA)-stabilized CuNCs (CuNCs-Fe(III)), which is in quenching state due to the electron transfer between CuNCs and Fe(3+), and then coating a protectable layer of hyaluronic acid (HA) on the surface of CuNCs-Fe(III) to form the final dual-locked nanoprobe (CuNCs-Fe(III)@HA). When the nanoprobe of CuNCs-Fe(III)@HA t...

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