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Unravelling the Role of LncRNA WT1-AS/miR-206/NAMPT Axis as Prognostic Biomarkers in Lung Adenocarcinoma

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成果类型:
期刊论文
作者:
Li, Wen;Liu, Yu;Li, Zi Jin;Shi, Yi;Deng, Jing*;...
通讯作者:
Chen, Zhu;Deng, Jing;Da, Fu
作者机构:
[Shi, Yi; Ma, Liang; Zeng, Xiao Xi; Liu, Yu; Rong, Duo Yan; Chen, Zhu; Li, Wen; Feng, Shan Shan] Hunan Univ Technol, Coll Life Sci & Chem, Zhuzhou 412007, Peoples R China.
[Deng, Jing; Li, Zi Jin; Li, Wen; Ren, Jia Li; Da, F; Da, Fu; Chen, Xiao Qi; Bai, Jie; Luo, Fei Jun] Cent South Univ Forestry & Technol, Coll Food Sci & Engn, Changsha 410004, Peoples R China.
[Yin, Hua Qun] Cent South Univ, Sch Resource Proc & Bioengn, Changsha 410083, Peoples R China.
[Da, Fu] Tongji Univ, Sch Med, Cent Lab Med Res, Shanghai Peoples Hosp 10, Shanghai 200072, Peoples R China.
通讯机构:
[Chen, Zhu] H
[Deng, J; Da, F] C
[Da, Fu] T
Hunan Univ Technol, Coll Life Sci & Chem, Zhuzhou 412007, Peoples R China.
Cent South Univ Forestry & Technol, Coll Food Sci & Engn, Changsha 410004, Peoples R China.
语种:
英文
关键词:
CeRNA network;LUAD;Prognosis;WT1-AS/miR-206/NAMPT axis
期刊:
Biomolecules
ISSN:
2218-273X
年:
2021
卷:
11
期:
2
页码:
1-17
基金类别:
This research was funded by the Natural Science Foundation of Hunan Province of China (2020JJ4278 and 2020JJ5127), the key program of the Hunan Provincial Department of science and technology (2020WK2020 and 2019NK2111), and the Program for Science & Technology Innovation Platform/Talents of Hunan Province (2019TP1029).
机构署名:
本校为通讯机构
院系归属:
食品科学与工程学院
摘要:
Lung cancer is the world’s highest morbidity and mortality of malignant tumors, with lung adenocarcinoma (LUAD) as a major subtype. The competitive endogenous RNA (ceRNA) regulative network provides opportunities to understand the relationships among different molecules, as well as the regulative mechanisms among them in order to investigate the whole transcriptome landscape in cancer pathology. We designed this work to explore the role of a key oncogene, MYC, in the pathogenesis of LUAD, and this study aims to identify important long noncodin...

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