Association of MMP9-1562C/T and MMP13-77A/G Polymorphisms with Non-Small Cell Lung Cancer in Southern Chinese Population

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成果类型：

期刊论文

作者：

Li, Wen;Jia, Ming Xi;Wang, Jian Hui;Lu, Jie Li;Deng, Jing*;...

通讯作者：

Deng, Jing;Tang, Jian Xin

作者机构：

[Deng, Jing; Tang, JX; Lu, Jie Li; Tang, Jian Xin; Liu, Cun; Jia, Ming Xi; Li, Wen] Hunan Univ Technol, Coll Life Sci & Chem, Key Lab Biol Nanomat & Devices, Zhuzhou 412007, Peoples R China.

[Li, Wen] Cent South Univ Forestry & Technol, Coll Food Sci & Engn, Natl Engn Lab Rice & Byprod Deep Proc, Changsha 410004, Hunan, Peoples R China.

[Wang, Jian Hui] Changsha Univ Sci & Technol, Sch Chem & Bioengn, Changsha 410114, Hunan, Peoples R China.

[Deng, Jing] Hunan Univ Technol, Coll Packaging & Mat Engn, Key Lab Adv Packaging Mat & Technol, Zhuzhou 412007, Peoples R China.

通讯机构：

[Deng, J; Tang, JX; Deng, Jing] H

Hunan Univ Technol, Coll Life Sci & Chem, Key Lab Biol Nanomat & Devices, Zhuzhou 412007, Peoples R China.

Hunan Univ Technol, Coll Packaging & Mat Engn, Key Lab Adv Packaging Mat & Technol, Zhuzhou 412007, Peoples R China.

语种：

英文

关键词：

MMP9;MMP13;single-nucleotide polymorphism;non-small cell lung cancer

期刊：

Biomolecules

ISSN：

2218-273X

年：

2019

卷：

期：

页码：

107-

DOI：

10.3390/biom9030107

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [1501538, 51774128]; Natural Science Foundation of Hunan Province of ChinaNatural Science Foundation of Hunan Province [2018JJ4061, 2018JJ2090, 2018JJ4009]; key program of Hunan Provincial Department of science and technology [2016NK2096]; Huxiang Youth talent Support Program [2015RS4051]; Scientific Research Fund of Hunan Provincial Education DepartmentHunan Provincial Education Department [17A055, 17C0487]; China of Postdoctoral Science FoundationChina Postdoctoral Science Foundation [2016T90769, 2016M592456, 2015M580707]; Green Packaging and Security Special Research Fund of China Packaging Federation [2017ZBLY14]; Zhu zhou Key Science & Technology Program of Hunan Province (2017)

机构署名：

本校为其他机构

院系归属：

食品科学与工程学院

摘要：

Background: Matrix metalloproteinases (MMPs) are capable of degrading and modifying most components of the extracellular matrix (ECM) and the basal membrane (BM), and play crucial roles in cancer invasion and metastasis. MMP gene expressions were regulated primarily at the transcriptional level, which was associated with tumor spread and patient prognosis. Polymorphisms in MMPs have been reported to be associated with non-small cell lung cancer (NSCLC). The objective of this study aim to evaluate the serum levels and polymorphisms of MMP-9 and ...

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Association of MMP9-1562C/T and MMP13-77A/G Polymorphisms with Non-Small Cell Lung Cancer in Southern Chinese Population

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