期刊论文

中文

菌物学报

1672-6472

2016

35

10

1250-1257

10.13346/j.mycosystema.150212

(NCET-13-1046):教育部“新世纪优秀人才支持计划”基金 (2014-04):湖南省高校学科带头人培养对象基金 (12K069,14K112):湖南省高校创新平台开放基金 :Supported by the Program for New Century Excellent Talents in University (NCET-13-1046),the Hunan Provincial University Academic Leader Training Object (2014-04),and the Scientific Research Fund of Hunan Provincial Education Department,China (12K069 & 14K112)

本校为第一机构

多糖和D-甘露醇是蛹虫草的重要药理活性成分。本文开展了蛹虫草在分批发酵过程中同时生产多糖和D-甘露醇的发酵动力学研究。利用Sigmoid函数构建了蛹虫草菌丝生长、糖基质消耗、多糖和D-甘露醇的非结构动力学模型,并根据Boltzmann方程拟合求解出各模型参数。结果显示,各模型的实测值和预测值拟合度较好。蛹虫草比生长速率在第1.0天达到最大值(μ_(max))1.244d~(-1);底物葡萄糖的比消耗速率在第0.6天达到最大值(q_(S, max))2.163d~(-1);多糖比合成速率在第2.0天达到最大值(q_(P, max))51.852mg/(g?d);D-甘露醇比合成速率在第0.99天左右达到最大值(q_(D, max))37.963mg/(g?d)。蛹虫草多糖的形成与...

Polysaccharides and D-mannitol are two of the key physiologically active components of Cordyceps militaris. The dynamic characters of simultaneous production of polysaccharides and D-mannitol by C. militaris in batch fermentation process were described. Unstructured kinetics of mycelial cell growth, glucose consumption, polysaccharides and D-mannitol were investigated based on Sigmoid model. The parameters of the model were determined by Boltzmann simulation, and the tested values matched well with the values predicted by the models. The maximu...