Molecular engineering of d-A-d-based non-linearity fluorescent probe for quick detection of thiophenol in living cells and tissues

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成果类型：

期刊论文

作者：

Zhou, Liyi*;Lin, Qinlu;Liu, Sihua;Tan, Yi;Sun, Hongyan

通讯作者：

Zhou, Liyi

作者机构：

[Zhou, Liyi; Lin, Qinlu] Cent South Univ Forestry & Technol Changsha, Coll Food Sci & Technol, Changsha 410004, Hunan, Peoples R China.

[Zhou, Liyi; Liu, Sihua] Hunan Univ Technol, Coll Life Sci & Chem, Zhuzhou 412007, Hunan, Peoples R China.

[Tan, Yi; Sun, Hongyan] City Univ Hong Kong, Dept Biol & Chem, 83 Tat Chee Ave, Kowloon, Hong Kong, Peoples R China.

[Zhou, Liyi] Cent South Univ Forestry & Technol, Changsha, Hunan, Peoples R China.

通讯机构：

[Zhou, Liyi] C

Cent South Univ Forestry & Technol, Changsha, Hunan, Peoples R China.

语种：

英文

关键词：

Fluorescent imaging;Thiophenols;Tissues;Two-photon

期刊：

Sensors and Actuators B-Chemical

ISSN：

0925-4005

年：

2017

卷：

244

页码：

958-964

DOI：

10.1016/j.snb.2017.01.079

基金类别：

Natural Science Foundation of China (NSFC)National Natural Science Foundation of China (NSFC) [21605046]

机构署名：

本校为第一且通讯机构

院系归属：

食品科学与工程学院

摘要：

Thiophenols are widely utilized for producing pesticides, polymers and pharmaceuticals. Studies have shown that prolonged exposure of human to thiolphenol can result in serious health problems such as significant damage of the central nervous system. Herein, we have developed a novel turn-on two-photon fluorescent probe TP-ASH for selective and sensitive detection of thiophenols. We first constructed a new two-photon dye by connecting a coumarin fluorophore and a naphthalene fluorophore through 2,5-disubstituted-1,3,4-oxadiazole ring to afford D-pi-A-pi-D-structure. Fluorescent studies showed ...

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Molecular engineering of d-A-d-based non-linearity fluorescent probe for quick detection of thiophenol in living cells and tissues

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