Molecular engineering of a mitochondrial-targeting two-photon in and near-infrared out fluorescent probe for gaseous signal molecules H2S in deep tissue bioimaging

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Zhou, Liyi*;Lu, Danqing;Wang, Qianqian;Liu, Sihua;Lin, Qinlu;...

通讯作者：

Zhou, Liyi

作者机构：

[Zhou, Liyi; Lin, Qinlu] Cent South Univ Forestry & Technol Changsha, Coll Food Sci & Technol, Changsha 410004, Hunan, Peoples R China.

[Zhou, Liyi; Liu, Sihua] Hunan Univ Technol, Coll Life Sci & Chem, Zhuzhou 412007, Hunan, Peoples R China.

[Wang, Qianqian; Lu, Danqing] Hunan Univ, Collaborat Innovat Ctr Chem & Mol Med, Coll Chem & Chem Engn, State Key Lab Chemobiosensing & Chemometr,Mol Sci, Changsha 410082, Hunan, Peoples R China.

[Sun, Hongyan] City Univ Hong Kong, Dept Biol & Chem, 83 Tat Chee Ave, Kowloon, Hong Kong, Peoples R China.

通讯机构：

[Zhou, Liyi] C

Cent South Univ Forestry & Technol Changsha, Coll Food Sci & Technol, Changsha 410004, Hunan, Peoples R China.

语种：

英文

关键词：

Bioimaging;Gaseous signal molecules;Mitochondrial-targeting;Near-infrared;Two-photon

期刊：

Biosensors and Bioelectronics

ISSN：

0956-5663

年：

2017

卷：

页码：

699-705

DOI：

10.1016/j.bios.2016.12.055

基金类别：

Natural Science Foundation of China (NSFC)National Natural Science Foundation of China (NSFC) [21605046]

机构署名：

本校为第一且通讯机构

院系归属：

食品科学与工程学院

摘要：

Hydrogen sulfide (H2S), one of the biologically important gaseous signal molecules, plays an essential role in diverse normal biochemical functions and pathological processes. Herein, an efficient two-photon in and near-infrared out mitochondria-targeting dye has been designed, synthesized and characterized. It is easily synthesized by the condensation reaction (C˭C) of 4-hydroxybenzaldehyde and 6-(diethylamino)−1,2,3,4-tetrahydroxanthylium (mitochondria-targeting), which possesses large two-photon action absorption cross-section ~160 g and h...

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Molecular engineering of a mitochondrial-targeting two-photon in and near-infrared out fluorescent probe for gaseous signal molecules H2S in deep tissue bioimaging

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