National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21275050, 21145001]; Hunan Provincial Natural Science Foundation of ChinaNatural Science Foundation of Hunan Province [13JJ1016]; Scientific Research Fund of Hunan Provincial Education DepartmentHunan Provincial Education Department [13A053]; Construct Program of the Key Discipline in Hunan Province; Foundation of the Science & Technology Department of Hunan Province [2016SK2020]
机构署名：
本校为其他机构
院系归属：
理学院
摘要：
A method is described for the determination of microRNA. It is based on the use of organic electrochemical transistors (OECTs) fabricated on a flexible poly(ethylene terephthalate) substrate. A gold electrode was modified with gold nanoparticles to immobilize the capture DNA probe and then served as the gate of the device. The detection of microRNA21 was realized by monitoring the change of the drain-source current after hybridization of capture DNA with microRNA21. Under optimal conditions, this biosensor exhibits good sensitivity and specific...
