Design, synthesis, and pesticidal activities of novel pyrimidin‐4‐amine derivatives containing trifluoroethyl sulfide moiety

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成果类型：

期刊论文

作者：

Li, Guojun;Liu, Aiping*;Xiao, Ting;Long, Chuyun;Ouyang, Wensen;...

通讯作者：

Liu, Aiping;Lan, SL;Xie, JJ

作者机构：

[Xie, Jianjun; Li, Guojun] Cent South Univ Forestry & Technol, Sch Mat Sci & Engn, Changsha, Peoples R China.

[Lan, Shilin; Ouyang, Wensen; Liu, Aiping; Long, Chuyun; Li, Jun; Li, Guojun; Li, Jianming; Xiao, Ting; Hu, Li] Hunan Res Inst Chem Ind, Natl Engn Res Ctr Agrochem, Changsha, Peoples R China.

[Liu, Aiping] Hunan Prov Key Lab Agrochem, Changsha, Peoples R China.

[Xiao, Ting] Changsha Univ Sci & Technol, Sch Chem & Chem Engn, Changsha, Peoples R China.

[Lan, Shilin; Liu, Aiping; Liu, AP; Lan, SL] Hunan Res Inst Chem Ind, Natl Engn Res Ctr Agrochem, Changsha 410007, Peoples R China.

通讯机构：

[Liu, AP; Lan, SL ] H

[Xie, JJ ] C

Hunan Res Inst Chem Ind, Natl Engn Res Ctr Agrochem, Changsha 410007, Peoples R China.

Cent South Univ Forestry & Technol, Sch Mat Sci & Engn, Changsha 410004, Peoples R China.

语种：

英文

关键词：

amine;pesticide;pyrimidin 4 amine derivative;sulfide;trifluoroethyl sulfide;unclassified drug;acaricidal activity;Article;Blumeria graminis;carbon nuclear magnetic resonance;controlled study;drug design;drug synthesis;EC50;elemental analysis;fungicidal activity;LC50;liquid chromatography-mass spectrometry;mass fragmentography;nonhuman;Puccinia;Tetranychus urticae

期刊：

Journal of Heterocyclic Chemistry

ISSN：

0022-152X

年：

2024

卷：

期：

页码：

611-626

DOI：

10.1002/jhet.4789

基金类别：

The authors thank the colleagues of the National Engineering Research Center for Agrochemicals, Hunan Research Institute of Chemical Industry. They also gratefully acknowledge the support of this work by the Key R&D Plan of Hunan Province (2022NK2053), Science and Technology Plan Project of Changsha (kh2201207).

机构署名：

本校为第一且通讯机构

院系归属：

材料科学与工程学院

摘要：

AbstractIn order to overcome the problem of pesticide resistance, it is necessary to discover novel pesticides with new mechanisms of action. Herein, a series of novel pyrimidin‐4‐amine derivatives containing trifluoroethyl sulfide moiety were designed and synthesized. Bioassays indicated that the title compounds synthesized possessed excellent acaricidal activity against Tetranychus urticae and fungicidal activity against Erysiphe graminis and Puccinia sorghi. Especially, the acaricidal activity of 5‐chloro‐6‐(difluoromethyl)‐N‐(2‐(2‐...

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Design, synthesis, and pesticidal activities of novel pyrimidin‐4‐amine derivatives containing trifluoroethyl sulfide moiety

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