The production of intracellular and extracellular triterpene acids of Ganoderma lucidum were studied in liquid fermentation. The results showed that the optimum fermentation conditions were as follows: culture temperature is 30 ℃, shaking speed is 160 r/min, liquid volume in flask (250 mL) is 80~100 mL, inoculum concentration is 10% (v/v), initial pH is 5.5~6.0, and culture time is 7d. Under theses conditions, the production yield of intracellular and extracellular triterpene a...