Xylitol was made from corncob with Candida tropicalis. The effects of the time of culture temperature, pH value, inoculation size and the culture volume in flask on xylitol yield were discussed. The process was optimized and analyzed with response surface methodology, and quadratic regression model was founded. The result showed that the xylitol yield was 76.35% as culture temperature was 32.4 ℃, pH value was 5.7, the culture volume in flask ...