期刊论文

中文

化学世界

0367-6358

2021

62

11

672-676

10.19500/j.cnki.0367-6358.20200705

湖南省教育厅资助科研（No.15A196）； 国家林业公益性行业科研专项（No.20120460103）资助项目；

本校为第一机构

采用紫外分光光度法研究姜黄素与羟丙基-β-环糊精（HP-β-CD）的超分子作用,探讨了温度和pH对包合过程形成常数的影响。研究表明,包合物中客体分子姜黄素与HP-β-CD形成的化学计量比为1∶1;随着温度增加,姜黄素-HP-β-CD包合物的形成常数减少,在20和40℃时包合物的形成常数分别为3 885.3和1 147.4 L/mol。30℃时,随着pH增大,形成常数先增大然后减小,pH值为5.0时,姜黄素-HP-β-CD包合物最稳定,形成常数为2 835.3 L/mol。热力学参数表明,姜黄素与HP-β-CD的超分子作用是一个焓驱动的自发放热过程。

UV/Vis was used to study the supramolecular interaction of curcumin and hydroxypropyl-β-cyclodextrin(HP-β-CD), and the influence of temperature and pH on the formation constant of inclusion process was investigated. The results showed that the stoichiometric ratio of curcumin to HP-β-CD in complex is 1∶1. The formation constant of curcumin-HP-β-CD inclusion complex decreased with the increase of temperature, and were 3 885.3 and 1 147.4 L/mol at 20 ℃ and 40 ℃, respectively. The formation constant firstly increased and then decreased with...