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The Potential Role of Vitamin E and the Mechanism in the Prevention and Treatment of Inflammatory Bowel Disease

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成果类型:
期刊论文
作者:
Wu, Qi;Luo, Yi;Lu, Han;Xie, Tiantian;Hu, Zuomin;...
通讯作者:
Luo, FJ
作者机构:
[Wu, Qi; Luo, Feijun; Lu, Han; Luo, FJ; Xie, Tiantian; Chu, Zhongxing; Hu, Zuomin] Cent South Univ Forestry & Technol, Hunan Key Lab Grain Oil Deep Proc & Qual Control, Hunan Key Lab Forestry Edible Resources Safety & P, Changsha 410004, Peoples R China.
[Luo, Yi] Cent South Univ, Xiangya Hosp, Dept Gastroenterol, Changsha 410008, Peoples R China.
[Luo, Feijun; Luo, FJ] Cent South Univ Forestry & Technol, Coll Food Sci & Engn, Changsha 410004, Peoples R China.
通讯机构:
[Luo, FJ ] C
Cent South Univ Forestry & Technol, Hunan Key Lab Grain Oil Deep Proc & Qual Control, Hunan Key Lab Forestry Edible Resources Safety & P, Changsha 410004, Peoples R China.
Cent South Univ Forestry & Technol, Coll Food Sci & Engn, Changsha 410004, Peoples R China.
语种:
英文
关键词:
vitamin E;inflammatory bowel disease;oxidative stress;anti-inflammation;intestinal barrier;gut microbiota
期刊:
Foods
ISSN:
2304-8158
年:
2024
卷:
13
期:
6
页码:
898-
基金类别:
Conceptualization, Data curation, Formal analysis, Methodology, Visualization, Writing—original draft, Writing—review and editing: Q.W.; Formal analysis: Y.L.; Visualization: T.X. and H.L.; Formal analysis, Writing—review and editing: Z.H. and Z.C.; Conceptualization, Data curation, Formal analysis, Methodology, Writing—original draft, Writing—review and editing, Funding acquisition, Supervision: F.L. All authors have read and agreed to the published version of the manuscript. The authors gratefully acknowledge the funds from the National Key R&D Program of China (No. 2022YFF1100200), the Natural Science Foundation of Hunan Province, China (Grant No. 2021JJ31075), the Program for Science & Technology Innovation Platform of Hunan Province (2019TP1029), Hunan Provincial Innovation Foundation For Postgraduate (No. CX20230765), Scientific Innovation Fund for Post-graduates of Central South University of Forestry and Technology (No. 2023CX02025).
机构署名:
本校为第一且通讯机构
院系归属:
食品科学与工程学院
摘要:
Inflammatory bowel disease (IBD) includes ulcerative colitis and Crohn's disease, and it is a multifactorial disease of the intestinal mucosa. Oxidative stress damage and inflammation are major risk factors for IBD. Vitamin E has powerful antioxidant and anti-inflammatory effects. Our previous work and other investigations have shown that vitamin E has a positive effect on the prevention and treatment of IBD. In this paper, the source and structure of vitamin E and the potential mechanism of vitamin E's role in IBD were summarized, and we also analyzed the status of vitamin E deficiency in pat...

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