This paper aimed to establish a method for measuring the concentration of amygdalin in almond skin. The optimization of detoxification also was finished. With Ultraviolet spectrometry, the maximum absorption wavelength determined at 219 nm , and the calibration curve was linear in a certain range(r^2=0.999 2) ,and with the standard of amygdalin as reference, amygdalin contents in samples were measured. Based on this method, the single factors and orthogonal optimization were used for the detoxification of soaking. The result is as follows : ...