A novel hybrid material derived from wood and acid nanospheres was synthesized by facile in-situ self-assembly of phosphotungstic acid (HPW) and triethylamine (TEA) at room temperature. The uniformly dispersed amphiphilic TEA-PW nanospheres furnished the wood with controlled particle sizes, and the acid capacity of the material could be altered by varying the molar ratio of HPW and TEA. Furthermore, the TEA-PW/wood hybrid had good anti-leach properties, which were attributed to the acid nanospheres' amphiphilicity. Notably, the hybrid material displayed excellent flame-retardant characteristic...