期刊论文

中文

食品与机械

1003-5788

2024

40

05

37-42,136

10.13652/j.spjx.1003.5788.2024.80356

湖南省自然科学基金(编号：2022JJ30587)；

本校为其他机构

目的:提高疏水性生物活性物质的水溶性和稳定性.方法:利用大米蛋白酶解物(RPH)和黄原胶(XG),以疏水性模型活性物质姜黄素(Cur)为输送对象,构建了RPH-XG-Cur纳米输送体系,测定并分析纳米粒子的包封效果、稳定性、抗氧化性以及形成机制.结果:R P H-XG-Cur纳米粒子的姜黄素包封率为78.40％,粒径74.78 nm,多分散指数0.36,Zeta电位—27.93 mV,添加黄原胶可显著提高纳米粒子的包封性能以及pH和离子强度稳定性;傅里叶红外光谱和荧光光谱分析表明氢键、静电相互作用和疏水相互作用均参与纳米粒子的形成.结论:RPH-XG纳米体系具有作为疏水性生物活性物质纳米输送载体的应用潜力.

Objective:To enhance the water solubility and stability of hydrophobic active substances.Methods:A nano-delivery system of rice protein hydrolysate(RPH)-xanthan gum(XG)-curcumin(Cur)was developed,wherein curcumin served as the delivery object,and the encapsulation efficiency,stability,antioxidant activity,and formation mechanism of the nanoparticles were determined and analyzed.Results:The encapsulation efficiency of RPH-XG-Cur nanoparticles reached 78.40％,with a particle size of 74.78 nm,PDI of 0.36,and Zeta potential of-27.93 mV.Remarkably,t...