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Neo-construction of a SO2-tunable near-infrared ratiometric fluorescent probe for high-fidelity diagnosis and evaluation hazards of Cd2+-induced liver injury

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成果类型:
期刊论文
作者:
Yuan, Xiaomin;Liu, Ting;Luo, Kun;Xie, Can;Zhou, Liyi
通讯作者:
Zhou, LY
作者机构:
[Luo, Kun; Xie, Can; Zhou, Liyi; Zhou, LY; Yuan, Xiaomin; Liu, Ting] Cent South Univ Forestry & Technol, Changsha 410004, Hunan, Peoples R China.
通讯机构:
[Zhou, LY ] C
Cent South Univ Forestry & Technol, Changsha 410004, Hunan, Peoples R China.
语种:
英文
关键词:
Liver injury;Near-infrared fluorescence;Oxidative stress;Sulfur dioxide (SO(2))
期刊:
Journal of Hazardous Materials
ISSN:
0304-3894
年:
2024
卷:
466
页码:
133653
基金类别:
Natural Science Foundation of China (NSFC) [21605046]; Hunan Provincial Natural Science Foundation of China [2017JJ3060, 2023JJ30988]
机构署名:
本校为第一且通讯机构
摘要:
Cadmium-contaminated water and food are seriously hazardous to the human health, especially liver injury. To understand the entanglement relationship between cadmium ion (Cd2+)-induced liver injury and the biomarker sulfur dioxide (SO2), a reliable bioanalytical tool is urgently needed, detecting SO2 to diagnose and evaluate the extent of liver injury in vivo. Herein, based on the F & ouml;rster resonance energy transfer (FRET) mechanism, a novel SO2-tunable NIR ratiometric fluorescent probe (SMP) was developed, it was used to diagnose and treat liver injury induced by Cd2+ in biosystems. Spec...

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