期刊论文

中文

食品工业科技

1002-0306

2019

40

17

121-126

10.13386/j.issn1002-0306.2019.17.020

“十三五”国家重点研发计划项目资助（2016YDF0600805）；

本校为第一机构

以碳酸钠改性制备的紫胶钠盐（SSC）用于包埋白藜芦醇（Res）,优化喷雾干燥制备工艺,获得具有pH响应性的SSC/Res微胶囊,促进白藜芦醇的吸收与利用。以壁材与芯材之比（壁-芯比）、进口温度和进料流量为考察因素,Res的包埋率及载药量为指标,在单因素实验的基础上利用响应面设计优化了喷雾干燥法制备SSC/Res微胶囊的工艺,通过FT-IR、SEM、TG-DSC技术对SSC/Res微胶囊的性能进行表征,并研究其在模拟人体消化过程中的释放性能。结果表明:SSC/Res微胶囊的优化工艺为壁-芯比3∶1 （g/g）,进口温度160℃,进料流量9.5 mL/min,此条件下Res的载药量为18.17%,与预测值一致。SSC/RES微胶囊为球体结构,表面光滑...

The shellac sodium salt(SSC)prepared by sodium carbonate modification was used to embed resveratrol(Res),optimize the spray drying preparation process,obtain pH-responsive SSC/Res microcapsules,and promote resveratrol’s absorption and utilization.Taking the ratio of wall material to core material(wall-core ratio),inlet temperature and feed flow rate as the investigation factors,the embedding rate and drug loading of Res were used as indicators.Based on the single factor experiment,the response surface design was used to optimize the preparatio...