Synthesis and fungicidal evaluation of novel 2-phenyl Thiazole derivatives

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成果类型：

期刊论文

作者：

Xiaofeng Guo;Han Wang;Bin Zhao;Zhijin Fan*;He Li

通讯作者：

Zhijin Fan

作者机构：

College of Forestry, Central South University of Forestry and Technology, Changsha 410004, PR China

State Key Laboratory of Elemento-Organic Chemistry, College of Chemistry, Nankai University, Tianjin 300071, PR China

College of Plant Protection, Hebei Agricultural University, Baoding 071001, PR China

Frontiers Science Center for New Organic Matter, College of Chemistry, Nankai University, Tianjin 300071, PR China

State Key Laboratory of Utilization of Woody Oil Resource, Central South University of Forestry and Technology, Changsha 410004, PR China

通讯机构：

[Zhijin Fan] S

State Key Laboratory of Elemento-Organic Chemistry, College of Chemistry, Nankai University, Tianjin 300071, PR China<&wdkj&>Frontiers Science Center for New Organic Matter, College of Chemistry, Nankai University, Tianjin 300071, PR China

语种：

英文

期刊：

Pesticide Biochemistry and Physiology

ISSN：

0048-3575

年：

2025

页码：

106668

DOI：

10.1016/j.pestbp.2025.106668

基金类别：

CRediT authorship contribution statement Xiaofeng Guo: Writing – review & editing, Writing – original draft, Project administration, Methodology, acquisition, Formal analysis, Data curation. Han Wang: Methodology. Bin Zhao: Writing – review & editing, Methodology, Data curation. Zhijin Fan: Writing – review & editing, Supervision, Resources, Project administration, acquisition, Data curation. He Li: Writing – review & editing, Supervision, Resources, acquisition, Data curation.

机构署名：

本校为第一机构

院系归属：

林学院

摘要：

Thiazole derivatives possess broad spectrum of biological activities, but only a few thiazole derivatives are developed as commercial fungicides compared to pyrazole and pyridine. In this study, we designed and synthesized 48 novel 2-phenyl thiazole derivatives to evaluate their potential as new fungicides. The results showed that compound 10c displayed excellent in vitro fungicidal activity as compared with positive control thifluzamide against Sclerotinia sclerotiorum , Botrytis cinerea and Rhizoctonia cerealis with corresponding EC 50 value ...

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Synthesis and fungicidal evaluation of novel 2-phenyl Thiazole derivatives

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