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Cladiella Octocorals: Enormous Sources of Secondary Metabolites with Diverse Structural and Biological Properties

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成果类型:
期刊论文
作者:
Ye-Qing Du;Lin-Fu Liang;Yue-Wei Guo;Ye-Qing Du Ye-Qing Du Ye-Qing Du;Lin-Fu Liang Lin-Fu Liang Lin-Fu Liang;...
通讯作者:
Liang, L.-F.;Guo, Y.-W.
作者机构:
School of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, 210023 China
State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555, Zu Chong Zhi Road, Zhangjiang Hi-Tech Park, Shanghai, 201203 China
Shandong Laboratory of Yantai Drug Discovery, Bohai rim Advanced Research Institute for Drug Discovery, Yantai, 264117 China
Open Studio for Druggability Research of Marine Natural Products, Pilot National Laboratory for Marine Science and Technology (Qingdao), 1 Wenhai Road, Aoshanwei, Jimo, Qingdao 266237 China
[Lin-Fu Liang; Lin-Fu Liang Lin-Fu Liang Lin-Fu Liang] College of Materials Science and Engineering, Central South University of Forestry and Technology, 498 South Shaoshan Road, Changsha, 410004 China
通讯机构:
[Lin-Fu Liang; Lin-Fu Liang Lin-Fu Liang Lin-Fu Liang] C
[Yue-Wei Guo; Yue-Wei Guo Yue-Wei Guo Yue-Wei Guo] S
School of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, 210023 China<&wdkj&>State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555, Zu Chong Zhi Road, Zhangjiang Hi-Tech Park, Shanghai, 201203 China<&wdkj&>Shandong Laboratory of Yantai Drug Discovery, Bohai rim Advanced Research Institute for Drug Discovery, Yantai, 264117 China<&wdkj&>Open Studio for Druggability Research of Marine Natural Products, Pilot National Laboratory for Marine Science and Technology (Qingdao), 1 Wenhai Road, Aoshanwei, Jimo, Qingdao 266237 China<&wdkj&>College of Materials Science and Engineering, Central South University of Forestry and Technology, 498 South Shaoshan Road, Changsha, 410004 China
语种:
英文
关键词:
anti-inflammatory activity;Cladiella;cytotoxicity;diterpenoids;steroids
期刊:
Chemistry & Biodiversity
ISSN:
1612-1872
年:
2023
卷:
20
期:
1
页码:
e202201065-
基金类别:
This research work was financially supported by the National Natural Science Foundation of China (NSFC) (Nos. 81991521 and 41876194), the National Key Research and Development Program of China (No. 2022YFC2804100) and the SKLDR/SIMM Project (No. SIMM2103ZZ‐06).
机构署名:
本校为通讯机构
院系归属:
材料科学与工程学院
摘要:
Marine octocorals belonging to the genus Cladiella, usually encountered on reefs in the Indo-Pacific region, have been proven to be rich sources of diverse secondary metabolites with intriguing structural features and promising bioactivities. In this review, 155 compounds from six unambiguously identified C. krempfi, C. australis, C. pachyclados, C. hirsuta, C. tuberculosa, C. conifera, together with several unidentified Cladiella spp. are summarized covering the literatures from 2006 to August 2022. It is noteworthy that diterpenoids dominated...

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