期刊论文

Kuang, ZF

英文

IEEE/ACM Transactions on Computational Biology and Bioinformatics

1545-5963

2023

20

5

3080-3092

10.1109/TCBB.2023.3248787

10.13039/501100001809-National Natural Science Foundation of China (Grant Number: 62072477, 61309027, 61702562 and 61702561) 10.13039/501100004735-Natural Science Foundation of Hunan Province (Grant Number: 2018JJ3888) Scientific Research Fund of Hunan Provincial Education Department (Grant Number: 18B197) National Key R&D Program of China (Grant Number: 2018YFB1700200) Hunan Key Laboratory of Intelligent Logistics Technology (Grant Number: 2019TP1015)

本校为第一且通讯机构

The circRNAs and miRNAs play an important role in the development of human diseases, and they can be widely used as biomarkers of diseases for disease diagnosis. In particular, circRNAs can act as sponge adsorbers for miRNAs and act together in certain diseases. However, the associations between the vast majority of circRNAs and diseases and between miRNAs and diseases remain unclear. Computational-based approaches are urgently needed to discover the unknown interactions between circRNAs and miRNAs. In this paper, we propose a novel deep learning algorithm based on Node2vec and Graph ATtention...