3D (three-dimensional) clusters mining from gene-sample-time (simply GST) microarray data can identify the samples corresponding to some phenotypes, such as diseases, and find the candidate genes correlated to phenotypes. When mining 3D clusters in 3D microarray data matrix, several objectives have to be optimized simultaneously, and often these objective are in conflict with each other. Therefore, it is very available to use a multi-objective evolutionary algorithms (MOEA) for finding 3D clusters in GST data. Based on E-dominance and sig...