期刊论文

Kuang, Zhufang

英文

Frontiers in Genetics

1664-8021

2020

11

514235

10.3389/fgene.2020.00272

This work was supported in part by the National Natural Science Foundation of China under Grants Nos. 61309027, 61702562, and 61702561, the Hunan Provincial Natural Science Foundation of China under Grants No. 2018JJ3888, the Scientific Research Fund of Hunan Provincial Education Department under Grant No. 18B197, the National Key R&D Program of China under Grant No. 2018YFB1700200, the Open Research Project of Key Laboratory of Intelligent Information Perception and Processing Technology (Hunan Province) under Grant No. 2017KF01, the Foundation Project of Hunan Internet of Things Society No. 2018-2, and the Hunan Key Laboratory of Intelligent Logistics Technology (2019TP1015).

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Interactions between genetic factors and environmental factors (EFs) play an important role in many diseases. Many diseases result from the interaction between genetics and EFs. The long non-coding RNA (lncRNA) is an important non-coding RNA that regulates life processes. The ability to predict the associations between lncRNAs and EFs is of important practical significance. However, the recent methods for predicting lncRNA-EF associations rarely use the topological information of heterogenous biological networks or simply treat all objects as the same type without considering the different and...