Tannin was extracted from persimmon leaf with microwave irradiation and combined-enzyme method, and the orthogonal test was employed to optimize the process. The results showed that under the condition of microwave power 400 W, microwave temperature 50 ℃, microwave irradiation time 10 min and the solvent content 40% ,the extraction yield of tannin was 90.12%. But the combined-enzyme method was 41.22% under the similar conditions. T...