Preparation and properties of hydrophobic films based on acetylated broken-rice starch nanocrystals for slow protein delivery

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Xiao, Huaxi;Yang, Fan;Lin, Qinlu*;Zhang, Qian;Tang, Weize;...

通讯作者：

Lin, Qinlu;Liu, Gao-Qiang

作者机构：

[Xiao, Huaxi; Liu, Gao-Qiang; Zhang, Lin; Xu, Dong; Lin, Qinlu] Cent South Univ Forestry & Technol, Natl Engn Lab Deep Proc Rice & Byprod, Changsha 410004, Hunan, Peoples R China.

[Xiao, Huaxi; Yang, Fan; Zhang, Qian; Tang, Weize; Zhang, Lin; Xu, Dong; Lin, Qinlu] Cent South Univ Forestry & Technol, Coll Food Sci & Engn, Changsha 410004, Hunan, Peoples R China.

[Liu, Gao-Qiang] Cent South Univ Forestry & Technol, Hunan Prov Key Lab Forestry Biotechnol, Changsha 410004, Hunan, Peoples R China.

[Liu, Gao-Qiang] Cent South Univ Forestry & Technol, Int Cooperat Base Sci & Technol Innovat Forest Re, Changsha 410004, Hunan, Peoples R China.

[Lin, Qinlu; Liu, GQ] 498 Southern Shaoshan Rd, Changsha 410004, Hunan, Peoples R China.

通讯机构：

[Lin, QL; Liu, GQ] 4

498 Southern Shaoshan Rd, Changsha 410004, Hunan, Peoples R China.

语种：

英文

关键词：

Acetylation;Broken-rice starch nanocrystals;Drug release

期刊：

International Journal of Biological Macromolecules

ISSN：

0141-8130

年：

2019

卷：

138

页码：

556-564

DOI：

10.1016/j.ijbiomac.2019.07.121

基金类别：

Scientific Research Foundation of Hunan Provincial Education DepartmentHunan Provincial Education Department [17A228, 17K106]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31571874, 81501619]; Intergovernmental Key Project of the International Science and Technology Cooperation Programme [2017YFE0108100]; Project of International Cooperation Base of Science and Technology Innovation on Forest Resource Biotechnology of Hunan Province [2018WK4008]; project of Chang-Zhu-Tan National Independent Innovation Demonstration Zone [2018XK2007]

机构署名：

本校为第一机构

院系归属：

食品科学与工程学院

生命科学与技术学院

摘要：

Native and acetylated broken-rice starches (nanocrystals) with different degrees of substitution (DS) and their corresponding films were individually prepared, and the drug release profiles, weight loss, solubility and dispersion and surface morphology were comparatively studied. Bovine serum albumin (BSA) was used as a model drug. Acetylated native starch (ANS) DS 2.58, acetylated starch nanocrystals (ASN) DS 0.98, ASN DS 1.86, and ASN DS 2.72 were observed to be very soluble in chloroform. BSA was released rapidly from the native rice starch (NS) and ANS DS 2.58 films. ASN with high DS signi...

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Preparation and properties of hydrophobic films based on acetylated broken-rice starch nanocrystals for slow protein delivery

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